Protein Alignment Polr1C and RPB3

DIOPT Version :10

• Sequence 1: NP_608885.1
• Gene: Polr1C / 33712
• FlyBaseID: FBgn0031657
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_012243.3
• Gene: RPB3 / 854791
• SGDID: S000001283
• Length: 318
• Species: Saccharomyces cerevisiae
• Alignment Length: 300
• Identity: 75/300 - (25%)
• Similarity: 133/300 - (44%)
• Gaps: 53/300 - (17%)

  Fly    38 KEKLHIKIVRNDEDGLEFDLIGVYPAIANAFRRLMLSDVPSMAIEKVYIYNNTSIIQDEVLAHRM 102
            :|...:||....:|.::|.|..|..|:||:.||:|::::|::||:.|.:..||:::.||.:|||:
Yeast     3 EEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRL 67

  Fly   103 GLLPLRADPRLFAYRTEESTEAGTEQDTLEFELKVKCSRRRDA----------GKDQSNFDDIYK 157
            ||:||::                .:.:.||:.....|....|.          |:.:|. .::|.
Yeast    68 GLIPLQS----------------MDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESEST-TNVYS 115

  Fly   158 NHKVYSGHLKWLPKGKQAQIYSESAVNCIHDDILIAQLRPGHELDLRLVAVKGLGRDHAKFSPVA 222
            ...|...:|  :.:.....|..:...|    .:||.:||.|.||.|..||.||:.::|||:.|.|
Yeast   116 KDLVIVSNL--MGRNIGHPIIQDKEGN----GVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAA 174

  Fly   223 TATYRLLPMIKLNREVTGKDAYLLQNCFSPGVIGIDENETAYVKDARYDTCSRNVYRYPQLNDAV 287
            ...:...|..||..    .|.:..|:         ...|....|:..|:.       .|...|..
Yeast   175 AIEFEYDPWNKLKH----TDYWYEQD---------SAKEWPQSKNCEYED-------PPNEGDPF 219

  Fly   288 TLARIRDHYIFSVESVGALKPDVIFLEAVKVLKRKCRALI 327
            ......|.:..:|||||::..|.:.:..:..|::|..:::
Yeast   220 DYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASIL 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Polr1C	NP_608885.1	RNAP_I_II_AC40	41..329	CDD:132910	74/296 (25%)
RPB3	NP_012243.3	RNAP_II_RPB3	6..265	CDD:132909	74/296 (25%)