DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3756 and RPAC43

DIOPT Version :9

Sequence 1:	NP_608885.1	Gene:	CG3756 / 33712	FlyBaseID:	FBgn0031657	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_176261.1	Gene:	RPAC43 / 842356	AraportID:	AT1G60620	Length:	385	Species:	Arabidopsis thaliana

Alignment Length:	370	Identity:	144/370 - (38%)
Similarity:	203/370 - (54%)	Gaps:	68/370 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 PLLYMEEYRV--KQDPQDYGLA------------DDVFSVQAFKEKLHIKIVRNDEDGLEFDLIG 59
            |.|.::..||  |:|...:..|            |:...::.|.|...:.::...|..:.||:||
plant    35 PHLELQRTRVVCKKDSNIHPTAITFSGAYSSMGVDNSVRLENFSEDFKVDVISLTETDMVFDMIG 99

  Fly    60 VYPAIANAFRRLMLSDVPSMAIEKVYIYNNTSIIQDEVLAHRMGLLPLRADPRLFAYRTEESTEA 124
            |:..|||||||::|:::|||||||||:.||||:|||||||||:||:|:.||||||.|.:|  .:.
plant   100 VHAGIANAFRRILLAELPSMAIEKVYVANNTSVIQDEVLAHRLGLIPIAADPRLFEYLSE--NDQ 162

  Fly   125 GTEQDTLEFELKVKCSR---RRDAGKDQSNFDDIYKNHKVYSGHLKWLPKGKQ------------ 174
            ..|::|:.|:|.|||.:   ||                ||.:..|||||.|.:
plant   163 PNEKNTIVFKLHVKCLKGDPRR----------------KVLTSELKWLPNGSELIKESGGSTTTP 211

  Fly   175 ---------AQIYSESAVNCIH---DDILIAQLRPGHELDLRLVAVKGLGRDHAKFSPVATATYR 227
                     ...:.|.|.|.|.   .|||||:|.||.|::|...||||:|:.|||:||||||.||
plant   212 KTYTSFNHSQDSFPEFAENPIRPTLKDILIAKLGPGQEIELEAHAVKGIGKTHAKWSPVATAWYR 276

  Fly   228 LLPMIKLNREVTGKDAYLLQNCFSPGVIGIDE----NETAYVKDARYDTCS--RNVYR-YPQLND 285
            :||.:.|.:|..||.|..|.......|..|::    .:.|.|  ||...||  |...| ..:..|
plant   277 MLPEVVLLKEFEGKHAEELVKVCPKKVFDIEDMGQGRKRATV--ARPRDCSLCRECIRDGVEWED 339

  Fly   286 AVTLARIRDHYIFSVESVGALKPDVIFLEAVKVLKRKCRALIDEI 330
            .|.|.|:::|:||::||.|:..|:|:|.||||:|:.||..:|.|:
plant   340 QVDLRRVKNHFIFTIESTGSQPPEVLFNEAVKILEDKCERVISEL 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3756	NP_608885.1	RNAP_I_II_AC40	41..329	CDD:132910	133/321 (41%)
CG3756	NP_608885.1	RPOLD	53..327	CDD:214766	131/307 (43%)
RPAC43	NP_176261.1	RNAP_I_II_AC40	81..383	CDD:132910	133/321 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	206	1.000	Domainoid score	I824
eggNOG	1	0.900	-	-		E1_COG0202
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3586
Inparanoid	1	1.050	217	1.000	Inparanoid score	I1218
OMA	1	1.010	-	-		QHG54254
OrthoDB	1	1.010	-	-		D834009at2759
OrthoFinder	1	1.000	-	-		FOG0003669
OrthoInspector	1	1.000	-	-		otm2888
orthoMCL	1	0.900	-	-		OOG6_102180
Panther	1	1.100	-	-	O	PTHR11800
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2540
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840