Protein Alignment Polr1C and polr2c

DIOPT Version :10

• Sequence 1: NP_608885.1
• Gene: Polr1C / 33712
• FlyBaseID: FBgn0031657
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_989124.1
• Gene: polr2c / 394729
• XenbaseID: XB-GENE-998258
• Length: 275
• Species: Xenopus tropicalis
• Alignment Length: 298
• Identity: 87/298 - (29%)
• Similarity: 148/298 - (49%)
• Gaps: 47/298 - (15%)

  Fly    43 IKIVRNDEDGLEFDLIGVYPAIANAFRRLMLSDVPSMAIEKVYIYNNTSIIQDEVLAHRMGLLPL 107
            ::|....::.::|.:.....||||:.||:.:::||::||:.|.|..|:|::.||.:|||:||:||
 Frog     9 VRITELTDENVKFIVENTDLAIANSIRRVFIAEVPTIAIDWVQIDANSSVLHDEFIAHRVGLIPL 73

  Fly   108 RADPRL--FAYRTEESTEAGTEQDTLEFELKVKCSRRRDAGKDQSNFDDIYKNHKVYSGHLKWLP 170
            .:|..:  ..|..:.:.:....:.::||.|.|:|:      :||:..   ..:..:.|.:|:.:|
 Frog    74 TSDDIVDKLQYSRDCTCDEFCPECSVEFTLDVRCN------EDQTRH---VTSRDLVSNNLRVIP 129

  Fly   171 KGKQAQIYSESAVN-----CIHDDILIAQLRPGHELDLRLVAVKGLGRDHAKFSPVATATYRLLP 230
                  :.|.|..|     ...|||||.:||.|.||.||..|.||.|::|||::|.|...:...|
 Frog   130 ------VTSRSRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDP 188

  Fly   231 MIKLNREVTGKDAYLLQNCFSPGVIGIDENETAYVKDARYDTCSRNVYRYPQLNDAVTLARIRDH 295
            ...|...|..|.....::.:|.    |||.|.    :|.||...:                 .:.
 Frog   189 DNALRHTVYPKPEEWPKSEYSE----IDEEEA----EAPYDPTGK-----------------PER 228

  Fly   296 YIFSVESVGALKPDVIFLEAVKVLKRKCRALIDEIEAE 333
            :.::|||.|:|:|:.|.|.|:..||:|...|..::..|
 Frog   229 FYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHE 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Polr1C	NP_608885.1	RNAP_I_II_AC40	41..329	CDD:132910	86/292 (29%)
polr2c	NP_989124.1	RNAP_II_RPB3	7..266	CDD:132909	86/296 (29%)