Protein Alignment Polr1C and Polr2c

DIOPT Version :10

• Sequence 1: NP_608885.1
• Gene: Polr1C / 33712
• FlyBaseID: FBgn0031657
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_001012491.1
• Gene: Polr2c / 361365
• RGDID: 1306935
• Length: 275
• Species: Rattus norvegicus
• Alignment Length: 298
• Identity: 86/298 - (28%)
• Similarity: 146/298 - (48%)
• Gaps: 47/298 - (15%)

  Fly    43 IKIVRNDEDGLEFDLIGVYPAIANAFRRLMLSDVPSMAIEKVYIYNNTSIIQDEVLAHRMGLLPL 107
            ::|....|:.::|.:.....|:||:.||:.:::||.:||:.|.|..|:|::.||.:|||:||:||
  Rat     9 VRITELTEENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPL 73

  Fly   108 RADPRL--FAYRTEESTEAGTEQDTLEFELKVKCSRRRDAGKDQSNFDDIYKNHKVYSGHLKWLP 170
            .:|..:  ..|..:.:.|....:.::||.|.|:|:  .|..:..::.|.|..:.:|       :|
  Rat    74 TSDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCN--EDQTRHVTSRDLISNSPRV-------IP 129

  Fly   171 -----KGKQAQIYSESAVNCIHDDILIAQLRPGHELDLRLVAVKGLGRDHAKFSPVATATYRLLP 230
                 :......|.|      .|||||.:||.|.||.||..|.||.|::|||::|.|...:...|
  Rat   130 VTSRNRDNDPNDYVE------QDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDP 188

  Fly   231 MIKLNREVTGKDAYLLQNCFSPGVIGIDENETAYVKDARYDTCSRNVYRYPQLNDAVTLARIRDH 295
            ...|...|..|.....::.:|.    :||:|:    .|.||...:                 .:.
  Rat   189 DNALRHTVYPKPEEWPKSEYSE----LDEDES----QAPYDPNGK-----------------PER 228

  Fly   296 YIFSVESVGALKPDVIFLEAVKVLKRKCRALIDEIEAE 333
            :.::|||.|:|:|:.|.|.|:..||:|...|..::..|
  Rat   229 FYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHE 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Polr1C	NP_608885.1	RNAP_I_II_AC40	41..329	CDD:132910	85/292 (29%)
Polr2c	NP_001012491.1	RNAP_II_RPB3	7..266	CDD:132909	85/296 (29%)