Protein Alignment CG3756 and Polr2c

DIOPT Version :9

• Sequence 1: NP_608885.1
• Gene: CG3756 / 33712
• FlyBaseID: FBgn0031657
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_033116.2
• Gene: Polr2c / 20021
• MGIID: 109299
• Length: 275
• Species: Mus musculus
• Alignment Length: 298
• Identity: 86/298 - (28%)
• Similarity: 146/298 - (48%)
• Gaps: 47/298 - (15%)

  Fly    43 IKIVRNDEDGLEFDLIGVYPAIANAFRRLMLSDVPSMAIEKVYIYNNTSIIQDEVLAHRMGLLPL 107
            ::|....|:.::|.:.....|:||:.||:.:::||.:||:.|.|..|:|::.||.:|||:||:||
Mouse     9 VRITELTEENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPL 73

  Fly   108 RADPRL--FAYRTEESTEAGTEQDTLEFELKVKCSRRRDAGKDQSNFDDIYKNHKVYSGHLKWLP 170
            .:|..:  ..|..:.:.|....:.::||.|.|:|:  .|..:..::.|.|..:.:|       :|
Mouse    74 TSDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCN--EDQTRHVTSRDLISNSPRV-------IP 129

  Fly   171 -----KGKQAQIYSESAVNCIHDDILIAQLRPGHELDLRLVAVKGLGRDHAKFSPVATATYRLLP 230
                 :......|.|      .|||||.:||.|.||.||..|.||.|::|||::|.|...:...|
Mouse   130 VTSRNRDNDPNDYVE------QDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDP 188

  Fly   231 MIKLNREVTGKDAYLLQNCFSPGVIGIDENETAYVKDARYDTCSRNVYRYPQLNDAVTLARIRDH 295
            ...|...|..|.....::.:|.    :||:|:    .|.||...:                 .:.
Mouse   189 DNALRHTVYPKPEEWPKSEYSE----LDEDES----QAPYDPNGK-----------------PER 228

  Fly   296 YIFSVESVGALKPDVIFLEAVKVLKRKCRALIDEIEAE 333
            :.::|||.|:|:|:.|.|.|:..||:|...|..::..|
Mouse   229 FYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHE 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3756	NP_608885.1	RNAP_I_II_AC40	41..329	CDD:132910	85/292 (29%)
		RPOLD	53..327	CDD:214766	82/280 (29%)
Polr2c	NP_033116.2	RNAP_II_RPB3	7..266	CDD:132909	85/296 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..226		7/47 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0202
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810