DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scox and sco2

DIOPT Version :9

Sequence 1:	NP_608884.1	Gene:	Scox / 33711	FlyBaseID:	FBgn0262467	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_001038697.1	Gene:	sco2 / 606683	ZFINID:	ZDB-GENE-041210-173	Length:	279	Species:	Danio rerio

Alignment Length:	222	Identity:	110/222 - (49%)
Similarity:	148/222 - (66%)	Gaps:	3/222 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 AQQPAIRHYAAPADSTKGKGP-ISWRSLAVIGALGAGG-VGFMLYVKSEKDEARMKERQRQLGKA 78
            |:|.|.....:|.....|... |..|:..|:..|..|| :|...||..||::....:|..||.|.
Zfish    45 ARQRAFYSQNSPKTPNPGSSAGIKLRTRLVVTLLFGGGIIGTWWYVHQEKEKRIQMQRLEQLRKV 109

  Fly    79 AIG-GSWELVDSQGAVRKSEDFLGKWLLIYFGFTHCPDICPDELEKMAAVVDEVEKSPQTPAVQP 142
            |:| |.:.|:|..|..|...||||.|:|:|||||||||||||||||:.:||..::|.|..|:|||
Zfish   110 ALGQGDFHLLDHTGQRRTKRDFLGHWVLLYFGFTHCPDICPDELEKLTSVVHILDKDPSLPSVQP 174

  Fly   143 IFITVDPERDSKEVVAKYVKEFSPKLLGLTGTVEQIRKVCKAFRVYFSAGPRDEDNDYIVDHTII 207
            :|||||||||....:|:|||:|.|:|:||||:.|::::..:.||||.|.||:|||.||||||:|:
Zfish   175 LFITVDPERDDVSAMARYVKDFHPRLVGLTGSAEEVKQAGRDFRVYASNGPKDEDGDYIVDHSIV 239

  Fly   208 MYLVNPDGEFVDYYGQNRDKDQCVASI 234
            :|||||||.|:|||.:.::..|...||
Zfish   240 IYLVNPDGLFIDYYNRMKNDTQIAESI 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scox	NP_608884.1	SCO1-SenC	81..217	CDD:396962	82/136 (60%)
sco2	NP_001038697.1	SCO	113..254	CDD:239266	84/140 (60%)
sco2	NP_001038697.1	AhpC-TSA	115..241	CDD:278975	73/125 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581891
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51910
OrthoDB	1	1.010	-	-		D1462537at2759
OrthoFinder	1	1.000	-	-		FOG0002408
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100983
Panther	1	1.100	-	-	O	PTHR12151
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1293
SonicParanoid	1	1.000	-	-		X1597
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.890