DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scox and Sco1

DIOPT Version :9

Sequence 1:	NP_608884.1	Gene:	Scox / 33711	FlyBaseID:	FBgn0262467	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_001035115.1	Gene:	Sco1 / 52892	MGIID:	106362	Length:	284	Species:	Mus musculus

Alignment Length:	213	Identity:	118/213 - (55%)
Similarity:	156/213 - (73%)	Gaps:	2/213 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 GPISWRSLAVIGALGAGGVGFMLYVKSEKDEARMKERQRQLGKAAIGGSWELVDSQGAVRKSEDF 99
            ||:||:|||:..|:|...:..|.|.|.||.|...|:|.|.:||..:||.:.|....|..:..:|:
Mouse    74 GPVSWKSLALTFAIGGSLLAGMKYFKKEKIEKLEKQRHRSIGKPLLGGPFSLTTHNGEPKTDKDY 138

  Fly   100 LGKWLLIYFGFTHCPDICPDELEKMAAVVDEVEKSPQTPAVQPIFITVDPERDSKEVVAKYVKEF 164
            ||:|:||||||||||||||:|||||..||:|::..|..|.:.|:|||:|||||:||.:|.|||||
Mouse   139 LGQWVLIYFGFTHCPDICPEELEKMIEVVEEIDSIPSLPNLTPLFITIDPERDTKEAIATYVKEF 203

  Fly   165 SPKLLGLTGTVEQIRKVCKAFRVYFSAGPRDEDNDYIVDHTIIMYLVNPDGEFVDYYGQNRDKDQ 229
            ||||:|||||.|:|..|.:|:|||:|.||:|||.||||||||||||:.|||||:||:|||:.|.:
Mouse   204 SPKLVGLTGTKEEIDGVARAYRVYYSPGPKDEDEDYIVDHTIIMYLIGPDGEFLDYFGQNKKKAE 268

  Fly   230 CVASILVNIAKWNSMNKK 247
            ...||..::.  :.|.|:
Mouse   269 IAGSIAAHMR--SHMKKR 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scox	NP_608884.1	SCO1-SenC	81..217	CDD:396962	86/135 (64%)
Sco1	NP_001035115.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	46..73
		Important for dimerization. /evidence=ECO:0000250	101..114		6/12 (50%)
		SCO	119..261	CDD:239266	90/141 (64%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838082
Domainoid	1	1.000	200	1.000	Domainoid score	I3047
eggNOG	1	0.900	-	-		E1_COG1999
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3374
Inparanoid	1	1.050	257	1.000	Inparanoid score	I3139
Isobase	1	0.950	-	0	Normalized mean entropy	S1273
OMA	1	1.010	-	-		QHG51910
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002408
OrthoInspector	1	1.000	-	-		oto92800
orthoMCL	1	0.900	-	-		OOG6_100983
Panther	1	1.100	-	-	LDO	PTHR12151
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1293
SonicParanoid	1	1.000	-	-		X1597
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740