Protein Alignment eIF3i and TIF34

DIOPT Version :10

• Sequence 1: NP_523478.1
• Gene: eIF3i / 33710
• FlyBaseID: FBgn0015834
• Length: 326
• Species: Drosophila melanogaster
• Sequence 2: NP_013866.1
• Gene: TIF34 / 855177
• SGDID: S000004754
• Length: 347
• Species: Saccharomyces cerevisiae
• Alignment Length: 328
• Identity: 148/328 - (45%)
• Similarity: 211/328 - (64%)
• Gaps: 6/328 - (1%)

  Fly     1 MRPLMLQGHERSITQIKYNREGDLLFSCSKDQKPNVWYSLNGERLGTYDGHQGAVWCLDVDWESR 65
            |:.:.|.||||.:||:|||:|||||||||||...:||||||||||||.|||.|.:|.:|||..::
Yeast     1 MKAIKLTGHERPLTQVKYNKEGDLLFSCSKDSSASVWYSLNGERLGTLDGHTGTIWSIDVDCFTK 65

  Fly    66 KLITGAGDMTAKIWDVEYGTVIASIPTKSSVRTSNFSFSGNQAAYSTDKAMGQ--SCELFLIDVR 128
            ..:||:.|.:.|:|||..|..:|:..:...|:...||..||......|..|..  |..::.|:..
Yeast    66 YCVTGSADYSIKLWDVSNGQCVATWKSPVPVKRVEFSPCGNYFLAILDNVMKNPGSINIYEIERD 130

  Fly   129 NADSSLSE--QEPTLRIPMTE--SKITSMLWGPLDETIITGHDNGNIAIWDIRKGQKVVDSGTDH 189
            :|...|::  :||..:|...|  ...|...|....:.||.||.:|.|:.:|:....:.|||...|
Yeast   131 SATHELTKVSEEPIHKIITHEGLDAATVAGWSTKGKYIIAGHKDGKISKYDVSNNYEYVDSIDLH 195

  Fly   190 SAGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTERPVNSAAISPIMDHVVLGGGQDA 254
            ...|:|||.|.|.|.|:|:|:||.:.|.|..:|..||.|:|:.|:|:|.|:|:.:.::|||||:|
Yeast   196 EKSISDMQFSPDLTYFITSSRDTNSFLVDVSTLQVLKKYETDCPLNTAVITPLKEFIILGGGQEA 260

  Fly   255 MEVTTTSTKAGKFDSRFFHLIYEEEFARLKGHFGPINSLAFHPDGKSYASGGEDGFVRVQTFDST 319
            .:|||||...|||::||:|.|:|||..|::|||||:|::|..|.|.||||||||||:|:..|:.:
Yeast   261 KDVTTTSANEGKFEARFYHKIFEEEIGRVQGHFGPLNTVAISPQGTSYASGGEDGFIRLHHFEKS 325

  Fly   320 YFE 322
            ||:
Yeast   326 YFD 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF3i	NP_523478.1	WD40	<6..313	CDD:441893	143/312 (46%)
		WD40 repeat	13..50	CDD:293791	28/36 (78%)
		WD40 repeat	56..91	CDD:293791	13/34 (38%)
		WD40 repeat	96..142	CDD:293791	13/49 (27%)
		WD40 repeat	151..186	CDD:293791	11/34 (32%)
		WD40 repeat	193..228	CDD:293791	17/34 (50%)
		WD40 repeat	234..284	CDD:293791	26/49 (53%)
		WD40 repeat	290..313	CDD:293791	14/22 (64%)
TIF34	NP_013866.1	WD40	<6..319	CDD:441893	143/312 (46%)
		WD40 repeat	13..49	CDD:293791	28/35 (80%)
		WD40 repeat	56..91	CDD:293791	13/34 (38%)
		WD40 repeat	96..148	CDD:293791	13/51 (25%)
		WD40 repeat	156..193	CDD:293791	12/36 (33%)
		WD40 repeat	240..290	CDD:293791	26/49 (53%)
		WD40 repeat	297..319	CDD:293791	14/21 (67%)