Protein Alignment Marcal1 and Smarca5

DIOPT Version :10

• Sequence 1: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_444354.2
• Gene: Smarca5 / 93762
• MGIID: 1935129
• Length: 1051
• Species: Mus musculus
• Alignment Length: 825
• Identity: 191/825 - (23%)
• Similarity: 309/825 - (37%)
• Gaps: 199/825 - (24%)

  Fly    32 PATNGKSTTSATGATQHANNGKSNPN---QPQA-----KSPLN------FYRSPTGEQKKINRSG 82
            |..:..|..||.||...::..|..|.   .|.|     ..|.:      |.....|:||:|....
Mouse    12 PPESAPSKPSAAGAGGSSSGNKGGPEGGAAPAAPCAAGSGPADTEMEEVFDHGSPGKQKEIQEPD 76

  Fly    83 PTPGDNKSSSFLNALK-AIKQTSNRELSRGAAHPYQRPNGGNERNKPTLSLSSDKEKPVAVLLGN 146
            ||..:...:...|..: .:|||   ||   .|| :.:|..   :..||..|   |.||....:..
Mouse    77 PTYEEKMQTDRANRFEYLLKQT---EL---FAH-FIQPAA---QKTPTSPL---KMKPGRPRVKK 128

  Fly   147 SITCNLYLISTHRFAAQTSGYHEQLVTVFK---NMPTKCYDGQTRIWSFDLSDYQSLKTHAADLK 208
            ....||..:..:|.........|:|:|...   |:.|:..|..:.:....|.|||
Mouse   129 DEKQNLLSVGDYRHRRTEQEEDEELLTESSKATNVCTRFEDSPSYVKWGKLRDYQ---------- 183

  Fly   209 PYVHMNGIPKKVLDLCGQPPVVPERSVLASIEPKLADQLMPFQQDGVCFAIAQKGRIMICDEMGL 273
                :.|:                            :.|:...::|:      .|  ::.|||||
Mouse   184 ----VRGL----------------------------NWLISLYENGI------NG--ILADEMGL 208

  Fly   274 GKTYQALAVADYFKD----DWPLLVCTTASTRDSWAKHIMDLLPKVPIHYVQVLNNNQ------- 327
            |||.|.:::..|.|.    ..|.:|....||..:|.......:|  .:..|.::.:.:
Mouse   209 GKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKKWVP--TLRSVCLIGDKEQRAAFVR 271

  Fly   328 --LYVGEAKVLITSYNMMERHEDKLMQRKFGFIIFDESHTLKNSKAKCTTTAKRLTDQAKRVVLL 390
              |..||..|.:|||.|:.:.:....:..:.:::.||:|.:||.|:|.:...:..  :....:||
Mouse   272 DVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREF--KTTNRLLL 334

  Fly   391 SGTPALSRPLELFTQLQMIDGKFMNFME-----FTTRYCDGKQSTFGWDANGQSNLEELKVILHL 450
            :|||..:...||::.|..:.....|..:     |.|..|.|.|..          :|.|.::|.
Mouse   335 TGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQKL----------VERLHMVLR- 388

  Fly   451 KYMLRRTKVEVLPQLAEKNRETVVLDPALV---WTNAETKETLDAFNKELKTAKGRATEEILLRF 512
            .::|||.|.:|...|..|....:.:..:.:   |......:.:|..|...|..|.|.. .||::.
Mouse   389 PFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAGKMDKMRLL-NILMQL 452

  Fly   513 ------------------YARTAEVKTRA----VCAYLKTLVKEQ-KKFIIFAHHRVMMDAISDF 554
                              |.....:.|.:    |...|...:||| .:.:||:....::|.:.|:
Mouse   453 RKCCNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDY 517

  Fly   555 LSGLKVHYIRIDGQTRSDHRSDSVDTFQKKSSCK-VALLSLKACNSGITLTAAEIIVFAELDWNP 618
            .......|.|:||||..|.|.||::.:.:.:|.| |.:||.:|...||.|..|::::..:.||||
Mouse   518 CMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNP 582

  Fly   619 STLAQAESRAHRIGQTKPVICRYLIAHNTADDIIWNMLKNKQE----VLSKVGIFAENLQK---- 675
            ....||..|||||||||.|.....|..||.::.|....:.|..    |:.:..:..:||.|
Mouse   583 QVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGRLVDQNLNKIGKD 647

  Fly   676 ---------ATHTAAPTSSHKIEE-----------------------------YFSPSTSTSL-- 700
                     |||..|...|...:|                             .|:..|.:|:
Mouse   648 EMLQMIRHGATHVFASKESEITDEDIDGILERGAKKTAEMNEKLSKMGESSLRNFTMDTESSVYN 712

  Fly   701 -EPERNSIKQYFSTIPAKEPPEQNNNTEMTKVNKAESDIAAFFND 744
             |.|....||..:.....|||::.        .||...:.|:|.:
Mouse   713 FEGEDYREKQKIAFTEWIEPPKRE--------RKANYAVDAYFRE 749

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	10/58 (17%)
		HepA	<233..666	CDD:440319	121/481 (25%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	54/226 (24%)
Smarca5	NP_444354.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..81		18/68 (26%)
		PLN03142	68..1011	CDD:215601	178/769 (23%)
		DEAH box	307..310		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1014..1051