Protein Alignment Marcal1 and SNF2

DIOPT Version :10

• Sequence 1: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_014933.3
• Gene: SNF2 / 854465
• SGDID: S000005816
• Length: 1703
• Species: Saccharomyces cerevisiae
• Alignment Length: 793
• Identity: 181/793 - (22%)
• Similarity: 299/793 - (37%)
• Gaps: 144/793 - (18%)

  Fly    13 KRIALAKLQAKKSQLLASAPATNGKSTTSATGATQHANNGKSNPNQPQAKSPLNFYRSPTGEQKK 77
            |...|.||:.||::.:|...:.| ||..:.....|...|.:.........:..|..|.   |||:
Yeast   587 KNHELLKLERKKTEAVARLKSMN-KSAINQYNRRQDKKNKRLKFGHRLIATHTNLERD---EQKR 647

  Fly    78 INRSGPTPGDNKSSSFLNALKAIKQTSNRELSRGAAHPYQRPNGGNERNKPTLSLSSDKEKPVAV 142
                    .:.|:...|.||||                       |:.......|...|:..:..
Yeast   648 --------AEKKAKERLQALKA-----------------------NDEEAYIKLLDQTKDTRITH 681

  Fly   143 LLGNSITCNLYLISTHRFAAQTSGYHEQLVTVFKNMPTKCYDGQTRIWSFDLSDYQSLKTHA--- 204
            ||..:   |.:|.|..|.......|.::::.......::..|        |||....:|...
Yeast   682 LLRQT---NAFLDSLTRAVKDQQKYTKEMIDSHIKEASEEVD--------DLSMVPKMKDEEYDD 735

  Fly   205 ADLKPYVHMNGIPKKVL-DLCGQPPVVPERSVLASIEPKLADQLMPFQQDGVCFAIAQKGRIM-- 266
            .|....|....:..::. |:..||.::            :...|..:|..|:.:.::.....:
Yeast   736 DDDNSNVDYYNVAHRIKEDIKKQPSIL------------VGGTLKDYQIKGLQWMVSLFNNHLNG 788

  Fly   267 -ICDEMGLGKTYQALAVADYFKD----DWPLLVCTTASTRDSWAKHIMDLLPKV-PIHYVQVLNN 325
             :.||||||||.|.:::..|..:    ..|.||....||..:|:.......|.: .|.:....|.
Yeast   789 ILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNE 853

  Fly   326 N-----QLYVGEAKVLITSYNMMERHEDKLMQRKFGFIIFDESHTLKNSKAKCTTTAKRLTDQAK 385
            .     ::..||..|::|::..:.:....|.:.|:..:|.||.|.:||:::|.:.|.........
Yeast   854 RKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADY 918

  Fly   386 RVVLLSGTPALSRPLELFTQLQMIDGKFMNFME-----FTTRYCDGKQSTFGWDANGQSNLEELK 445
            |:: |:|||..:...||:..|..:..|..|.::     |.|.:.    :|.|.|....|..|.|.
Yeast   919 RLI-LTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFA----NTGGQDKIELSEEETLL 978

  Fly   446 VILHL-----KYMLRRTKVEVLPQLAEKNRETVVLDPALVW-----------------TNAETKE 488
            ||..|     .::|||.|.:|..:|.:|..:.|....:.:.                 .|.:...
Yeast   979 VIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLFIGDQNNKKMV 1043

  Fly   489 TLDAFNKELKTAK------------------GRATEEILLRFYARTAEVKTRAVCAYLKTLVKEQ 535
            .|..||.::...|                  .|.|.:.:.| .|...|:..|    .|..|....
Yeast  1044 GLRGFNNQIMQLKKICNHPFVFEEVEDQINPTRETNDDIWR-VAGKFELLDR----ILPKLKATG 1103

  Fly   536 KKFIIFAHHRVMMDAISDFLSGLKVHYIRIDGQTRSDHRSDSVDTFQKKSS---CKVALLSLKAC 597
            .:.:||.....:||.:.|||..:.:.|:|:||.|:||.||:.:..|....|   |  .:||.:|.
Yeast  1104 HRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLC--FILSTRAG 1166

  Fly   598 NSGITLTAAEIIVFAELDWNPSTLAQAESRAHRIGQTKPVICRYLIAHNTADDIIWNMLKNKQEV 662
            ..|:.|..|:.::..:.||||....||:.|||||||...|....||..|:.:::|......|.::
Yeast  1167 GLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDI 1231

  Fly   663 LSKV---GIFAENLQKATHTAAPTSSHKIEEYFSPSTSTSLEPERNSIKQYFSTIPAKEPPEQNN 724
            ..||   |.|..........|...|....||.......:.:|.|........:.|.|:      |
Yeast  1232 DGKVIQAGKFDNKSTSEEQEALLRSLLDAEEERRKKRESGVEEEEELKDSEINEILAR------N 1290

  Fly   725 NTEMTKVNKAESD 737
            :.||..:.:.:.|
Yeast  1291 DEEMAVLTRMDED 1303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	8/58 (14%)
		HepA	<233..666	CDD:440319	122/493 (25%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	58/231 (25%)
SNF2	NP_014933.3	QLQ	248..281	CDD:462622
		HSA	<617..656	CDD:462194	8/49 (16%)
		PLN03142	650..>1297	CDD:215601	163/710 (23%)
		SnAC	1303..1369	CDD:464219	1/1 (100%)
		Bromo_SNF2	1550..1652	CDD:99950