Protein Alignment Marcal1 and smarca2

DIOPT Version :10

• Sequence 1: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_031746549.1
• Gene: smarca2 / 734002
• XenbaseID: XB-GENE-1013843
• Length: 1606
• Species: Xenopus tropicalis
• Alignment Length: 848
• Identity: 186/848 - (21%)
• Similarity: 331/848 - (39%)
• Gaps: 211/848 - (24%)

  Fly     6 SSEIAEKKRIALAKLQAKKSQLLASAPATNGKSTTSATGATQHANNGKSNPNQPQAKS-PLNFYR 69
            :|.:.|.|:...||.:.||.:  ......|.:...|..|.     :|:......|... |:....
 Frog   558 TSLVWEHKKAQAAKEKKKKKK--KKKAEENAEGVGSGLGM-----DGELIDESSQMSDLPVKVIH 615

  Fly    70 SPTGEQKKINRSGPTPGDNKSSSFLNALKAIKQTSNRELSRGAAHPYQRPNGGNERNKPTLSLSS 134
            :.||   |:..:...|..::..::|. :....:.:.|..|.|::..|:......|.::    |.:
 Frog   616 TETG---KVLLAPEAPKASQLETWLE-MNPGYEVAPRSDSEGSSSEYEEEEDEEESSR----LDT 672

  Fly   135 DKEKPVAVLLGNSITCNLYLISTHRFAAQTSGYHE--QLVTVFKNMPTKCYDGQTRIWSFDLSDY 197
            :::|.:.:...:::.                  |:  |::...|.               |:.|.
 Frog   673 EEKKRLGLNTEDNVK------------------HDAKQIIETAKQ---------------DVDDE 704

  Fly   198 QSLKTHAADLKPYVHMNGIPKKVLDLCGQPPVVPERSVLASIEPKLADQLMPFQQDGVCFAIAQK 262
            .|::..|...:.|.   |:...|.:     .|..:.|:|      :...|..:|..|:.:.::..
 Frog   705 YSMQEDARQSQSYY---GVAHAVTE-----RVEKQSSLL------INGSLKHYQIQGLEWMVSLF 755

  Fly   263 GRIM---ICDEMGLGKTYQALAVADYFKD----DWPLLVCTTASTR-------DSWAKHIMDLLP 313
            ...:   :.||||||||.|.:|:..|..:    :.|.|:....||.       |.||..::.:..
 Frog   756 NNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWLYEFDKWAPSVVKIAY 820

  Fly   314 K---------VPIHYVQVLNNNQLYVGEAKVLITSYNMMERHEDKLMQRKFGFIIFDESHTLKNS 369
            |         ||          ||..|:..||:|:|..:.:.:..|.:.::.::|.||.|.:||.
 Frog   821 KGTPAMRRSLVP----------QLRTGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNH 875

  Fly   370 KAKCTTTAKRLTDQ-AKRVVLLSGTPALSRPLELFTQLQMIDGKFMNFMEFTT-RYCDGKQSTFG 432
            ..|.|....  |.. |.|.:||:|||..::..||:.        .:||:..|. :.|    |||.
 Frog   876 HCKLTQVLN--THYVAPRRILLTGTPLQNKLPELWA--------LLNFLLPTIFKSC----STFE 926

  Fly   433 WDANG-------QSNLEELKVILHLK--------YMLRRTKVEVLPQLAEKNRETVVLDPA---- 478
            ...|.       :.:|.|.:.||.::        ::|||.|.||..||.||....:..|.:
 Frog   927 QWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQK 991

  Fly   479 LVWTNAETKETLDAFNKELKTAKGRATEEILLRFYARTAEVKTRAVC-----------------A 526
            :::.:.:.|..|.....| |..||:...:.|:     ...::.|.:|                 .
 Frog   992 ILYRHMQAKGILLTDGSE-KDKKGKGGAKTLM-----NTIMQLRKICNHPFIFQHIEESFAEHLG 1050

  Fly   527 YLKTLV------KEQKKFIIF---------AHHRV--------MMDAISDFLSGLKVHYIRIDGQ 568
            |...::      :...||.:.         .:|||        :|..:.|:.:.....|:|:||.
 Frog  1051 YSNGIINGPDLYRTSGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGT 1115

  Fly   569 TRSDHRSDSVDTFQKKSS-CKVALLSLKACNSGITLTAAEIIVFAELDWNPSTLAQAESRAHRIG 632
            |:|:.|:..:..|.::.| ..:.|||.:|...|:.|.||:.:|..:.||||....||:.||||||
 Frog  1116 TKSEDRASLLKRFNEEGSPFFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIG 1180

  Fly   633 QTKPVICRYLIAHNTADDIIWNMLKNKQEVLSKV---GIFAENLQKATHTAAPTSSHK------- 687
            |...|....|...|:.::.|....|.|..|..||   |:|.:.          :|||:
 Frog  1181 QQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQK----------SSSHERRAFLQA 1235

  Fly   688 IEEYFSPSTSTSLEPERNSIKQYFSTIPAKEPPEQNNNTEMTKVNKAESDIAAFFNDDDDEAFLE 752
            |.|:...:.|...:.....|.|..::....|.|:.....:|         ||.  ::::.|.|:.
 Frog  1236 ILEHEEQNESQKKDDLSGDISQEGASQEEDEVPDDETLNQM---------IAR--HEEEFELFMR 1289

  Fly   753 LDI 755
            :|:
 Frog  1290 MDL 1292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	8/57 (14%)
		HepA	<233..666	CDD:440319	130/517 (25%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	63/248 (25%)
smarca2	XP_031746549.1	Atrophin-1	31..>467	CDD:460830
		QLQ	175..209	CDD:462622
		HSA	453..525	CDD:214727
		BRK	605..648	CDD:462196	7/46 (15%)
		PLN03142	697..>1218	CDD:215601	141/579 (24%)
		DEXHc_SMARCA2	717..967	CDD:350821	71/287 (25%)
		SnAC	1293..1360	CDD:464219	186/848 (22%)
		Bromo_SNF2L2	1416..1522	CDD:99947