Protein Alignment Marcal1 and Rad54b

DIOPT Version :10

• Sequence 1: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001034645.1
• Gene: Rad54b / 623474
• MGIID: 3605986
• Length: 886
• Species: Mus musculus
• Alignment Length: 650
• Identity: 151/650 - (23%)
• Similarity: 248/650 - (38%)
• Gaps: 171/650 - (26%)

  Fly   239 IEPKLADQLMPFQQDGVCF---------AIAQKGRIMICDEMGLGKTYQALAVADYFKDDWPL-- 292
            |:|.|...|.|.|:||:.|         |:.:.|.| :.||||||||.|.:::.      |.|
Mouse   266 IDPHLVHHLRPHQKDGIIFLYECVMGMRAVGKCGAI-LADEMGLGKTLQCISLI------WTLQC 323

  Fly   293 -------------LVCTTASTRDSWAKHIMDLLPKVPI--------HYVQVLNNNQLYVGEAKVL 336
                         |:.|..|..::|.|.....|....|        |.|:...|:..:    .||
Mouse   324 QGPYGGKPVIKKTLIVTPGSLVNNWRKEFQKWLGSERIKIFTVDQDHKVEEFINSTFH----SVL 384

  Fly   337 ITSYNMMERHEDKLMQRKFGFIIFDESHTLKNSKAKCTTTAKRLTDQAKRVVLLSGTPALSRPLE 401
            |.||.|:.|..|::....||.:|.||.|.||||..|.||....|:  .::.|:|:|||..:...|
Mouse   385 IISYEMLLRSLDQIKTIPFGLLICDEGHRLKNSSIKTTTALSSLS--CEKTVILTGTPVQNDLQE 447

  Fly   402 LF---------------------------------------------TQLQMIDGKFM--NFMEF 419
            .|                                             |:|..:.|:|:  ...|.
Mouse   448 FFALVDFVNPGILGSLSSYRKIYEEPIIISREPSSSKEERELGERRATELTRLTGRFILRRTQEV 512

  Fly   420 TTRYCDGKQSTFGWDANGQSNLEELKVILHLKYMLRRTKVE-VLPQLAEKNRETVVL-------- 475
            ..:|...|.....:...|     .|::.|:.| :||...|. .|..|.|.:...:.:
Mouse   513 INKYLPPKIENVVFCRPG-----ALQIELYRK-LLRSQSVRFCLQGLLENSAHLICIGALKKLCN 571

  Fly   476 DPALVWTNAETKETLDAF--NKELKTAKGRATEEILLRFYA-----RTAEVKTRAVCAYLKTL-- 531
            .|.|::::.:.||...:.  |:|....:|     :|..|.|     :.:|.::..:...:|.|
Mouse   572 HPCLLFSSVKGKEFSSSCEENEERNLCQG-----LLSVFPAGYNPLQFSEEESGKLQVLVKLLAV 631

  Fly   532 ---VKEQKKFIIFAHHRVMMDAISDFLSGLKVHYIRIDGQTRSDHRSDSVDTFQKKSSCK-VALL 592
               ::..:|.|:.:::|..::.:.:..........|:||||....|...||:|..|.|.. :.||
Mouse   632 IHELRPTEKVILVSNYRQTLNVLEEVCKRHGYACARLDGQTPVSQRQHIVDSFNSKYSTDFIFLL 696

  Fly   593 SLKACNSGITLTAAEIIVFAELDWNPSTLAQAESRAHRIGQTKPVICRYLIAHNTADDIIWNMLK 657
            |.||...|:.|.....::..::||||:|..||.||..|.||..||....|:...|.::.|:....
Mouse   697 SSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKHPVHIYRLLTTGTIEEKIYQRQI 761

  Fly   658 NKQ--------------------EVLSKVGIFAENLQKATH-----------------TAAPTSS 685
            :||                    |.|..:....|:....||                 :..|.:|
Mouse   762 SKQGLSGAVVDLTRSSEHIQFSVEELKNLFTLHESSHCVTHDLLDCECTGEKGHTEDASEGPVAS 826

  Fly   686 HKIEEYFSPSTSTSLEP-ERNSIKQYFSTIPAKEPPEQNNNTEMTKVNKAESDIAAFFNDDDDEA 749
            .:.:  |.|..|.:|.| ..:.:||:      |.....:.|.....:.:...:::.||.:..::|
Mouse   827 RQCQ--FGPQKSDALRPLSMSQLKQW------KHFSGDHLNLPDPFLERIRENVSFFFQNITNQA 883

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Marcal1	NP_608883.1	HARP	160..216	CDD:462166
		HepA	<233..666	CDD:440319	134/547 (24%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	71/287 (25%)
Rad54b	NP_001034645.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..95
		HepA	<274..772	CDD:440319	129/521 (25%)
		DEXHc_RAD54B	274..508	CDD:350824	63/246 (26%)
		DEGH box	409..412		2/2 (100%)