DRSC/TRiP Functional Genomics Resources

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Protein Alignment Marcal1 and chd6

DIOPT Version :10

Sequence 1:NP_608883.1 Gene:Marcal1 / 33709 FlyBaseID:FBgn0031655 Length:755 Species:Drosophila melanogaster
Sequence 2:XP_699360.5 Gene:chd6 / 570753 ZFINID:ZDB-GENE-130530-559 Length:2953 Species:Danio rerio


Alignment Length:674 Identity:163/674 - (24%)
Similarity:261/674 - (38%) Gaps:168/674 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   218 KKVLDLCGQPPVVPE--RSVLASIEPKLADQLMPFQQDG---VCFAIAQKGRIMICDEMGLGKTY 277
            |||.::......:||  :.:..|.:.:..:||..:|.:|   :.|....:...::.||||||||.
Zfish   446 KKVPEMKHVERPLPEQWQKLEKSRDYRNGNQLREYQLEGMNWLLFNWYNRKNCILADEMGLGKTI 510

  Fly   278 QALA-VADYFKDD--WPLLVCTTASTRDSWAK-------------HIMDLLPKVPIHYVQVLNNN 326
            |::. :.:.|...  .|.|:....||..:|.:             |...:..::.:.|.....:.
Zfish   511 QSITFLYEIFLMGLRGPFLIIAPLSTITNWEREFRTWTEMNVIVYHGSQISRQMILQYEMYHRDE 575

  Fly   327 Q--LYVGEAKV--LITSYNMMERHEDKLMQRKFGFIIFDESHTLKNSKAKCTTTAKRLTDQAKRV 387
            |  :..||.|.  :||::.|:.....:|.:..:..::.||:|.|||...|.....|.:..:.|  
Zfish   576 QGNIMSGEFKFQGVITTFEMIMADCPELKKINWRCVVIDEAHRLKNRNCKLLEGLKLMNLEHK-- 638

  Fly   388 VLLSGTPALSRPLELFTQLQMIDGKFMNFME-----FTTRYCDGKQSTFGWDANGQSNLEELKVI 447
            |||:|||..:...|||:        .:||:|     ..|.:.:    .|| |...:..:::|:.|
Zfish   639 VLLTGTPLQNSVEELFS--------LLNFLEPSQFPSETTFLE----EFG-DLKTEEQVKKLQAI 690

  Fly   448 LHLKYMLRRTKVEVLPQLAEKNRETVVLDPALVWTNAETKETLDAFNKELK-TAKG--------- 502
            |. ..||||.|.:|...||.| .||::   .:..||.:.|.......|... .|||         
Zfish   691 LK-PMMLRRLKDDVEKNLAPK-EETII---EVELTNIQKKYYRAILEKNFAFLAKGANQHNMPNL 750

  Fly   503 -----------------RATEEILLRFYART-----AEVKTRAVCAYLKTLVKEQK--------- 536
                             ...||.:|..:.:|     |:.:.:|:......||...|         
Zfish   751 INTMMELRKCCNHPYLITGAEEKILESFRKTYSSDAADFQLQAMIQAAGKLVLIDKLLPKLLAGG 815

  Fly   537 -KFIIFAHHRVMMDAISDFLSGLKVHYIRIDGQTRSDHRSDSVDTFQKKSSCK-VALLSLKACNS 599
             |.::|:.....:|.:.|:|...:..|.||||:.|.:.|..::|.|.|..|.: |.||..:|...
Zfish   816 HKVLVFSQMVRCLDILEDYLIQRRYTYERIDGRVRGNLRQAAIDRFSKVDSDRFVFLLCTRAGGL 880

  Fly   600 GITLTAAEIIVFAELDWNPSTLAQAESRAHRIGQTKPVICRYLIAHNTAD--------------- 649
            ||.||||:..:..:.||||....||::|.|||||:|.|....||..|:.:               
Zfish   881 GINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDK 945

  Fly   650 ----DIIWNMLKNKQEVLSKVGI---------------------FAEN-----LQKATHTAAPTS 684
                ||......|..:.|||:.:                     |.|.     ||:.|.|....|
Zfish   946 AVLQDINRKGSLNGVQQLSKMEVEDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTQTITIQS 1010

  Fly   685 SHK-----IEEYFSPSTSTSLEPERNSIKQYFSTIPAKEPPEQNNNTEMTKVNKAESDIAAF--- 741
            ..|     ...:.|....|.:..:..:..|.::.|           .|:...:|||.:....   
Zfish  1011 EGKGSTFAKASFVSSGNRTDISLDDPNFWQKWAKI-----------AELEIDSKAEKESLVIDTP 1064

  Fly   742 -----------FNDDDDEAFLELD 754
                       |.||:...|.|||
Zfish  1065 RVRKQTRHYNSFEDDELMEFSELD 1088

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Marcal1NP_608883.1 HARP 160..216 CDD:462166
HepA <233..666 CDD:440319 134/522 (26%)
DEXHc_HARP_SMARCAL1 247..456 CDD:350768 59/236 (25%)
chd6XP_699360.5 CD1_tandem_CHD5-9_like 303..369 CDD:349315
CD2_tandem_CHD5-9_like 388..446 CDD:349310 163/674 (24%)
PLN03142 476..>1077 CDD:215601 150/631 (24%)
DEXHc_CHD6 477..698 CDD:350816 59/236 (25%)
BRK 2561..2604 CDD:462196
PHA03255 2716..>2789 CDD:165513
Blue background indicates that the domain is not in the aligned region.

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