Protein Alignment Marcal1 and chd4b

DIOPT Version :10

• Sequence 1: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_021322613.1
• Gene: chd4b / 560622
• ZFINID: ZDB-GENE-030131-4532
• Length: 1953
• Species: Danio rerio
• Alignment Length: 685
• Identity: 163/685 - (23%)
• Similarity: 274/685 - (40%)
• Gaps: 147/685 - (21%)

  Fly   175 FKNMPTKCYDGQTRIW---SFDLSDYQSLKTH---------AADLKPYVHMNGIPKKVLDLCGQP 227
            ::::|   ||..|  |   ..|:.|:::.|.|         ..:.:|...|..:..:..:   :|
Zfish   654 WRDLP---YDQST--WESEDMDVPDFETYKQHYWNHRELMLGEEGRPGKKMKKVKVRKTE---RP 710

  Fly   228 PVVP--ERSVLASIEPKLADQ----LMPFQQDG---VCFAIAQKGRIMICDEMGLGKTYQ-ALAV 282
            |..|  :.::....:|...|.    |.|:|.:|   :.|:.||....::.||||||||.| |:.:
Zfish   711 PANPVVDPTIKFDRQPDYLDSTGGTLHPYQLEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFL 775

  Fly   283 ADYFKD---DWPLLVCTTASTRDSWAKHIMDLLPKV-PIHYV------QVLNNNQLYV------G 331
            ...:|:   ..|.||....||..:|.:......|.: .:.||      .|:..|:...      |
Zfish   776 YSLYKEGHSKGPFLVSAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAVIRENEFTFEDNAIRG 840

  Fly   332 EAK-------------VLITSYNMMERHEDKLMQRKFGFIIFDESHTLKNSKAKCTTTAKRLTDQ 383
            ..|             ||:|||.::...:..|....:..::.||:|.|||:::|..........|
Zfish   841 GKKASKMKKEAAVKFHVLLTSYELITIDQAILGSIDWACLVVDEAHRLKNNQSKFFRVLNNYPLQ 905

  Fly   384 AKRVVLLSGTPALSRPLELFTQLQMI-DGKFMNFMEFTTRYCDGKQSTFGWDANGQSNLEELKVI 447
            .|  :||:|||..:...|||..|..: ..:|.|...|...:.|..:         :..:::|..:
Zfish   906 HK--LLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADIAK---------EDQIKKLHDM 959

  Fly   448 LHLKYMLRRTKVEVLPQLAEKNRETVV---LDPA-------LVWTNAETKETLDAFNK------- 495
            |. .:||||.|.:|...:..|. |.:|   |.|.       ::..|.|...|....|:
Zfish   960 LG-PHMLRRLKADVFKHMPSKT-ELIVRVELSPMQKKYYKYILTRNFEALNTRGGGNQVSLLNVV 1022

  Fly   496 -ELK----------TAKGRATE--EILLRFYARTAEVKTRAVCAYLKTLVKEQK----KFIIFAH 543
             :||          ||   |||  ::....|..:|..|.......|..::|:.|    :.:||:.
Zfish  1023 MDLKKCCNHPYLFPTA---ATEAPKMPNGMYDGSALTKASGKLMLLFKMLKKLKEGGHRVLIFSQ 1084

  Fly   544 HRVMMDAISDFLSGLKVHYIRIDGQTRSDHRSDSVDTFQKKSSCK-VALLSLKACNSGITLTAAE 607
            ...|:|.:.|||......|.||||......|.:::|.|....:.: |.|||.:|...||.|..|:
Zfish  1085 MTKMLDLLEDFLENEGYKYERIDGGVTGGMRQEAIDRFNAPGAPQFVFLLSTRAGGLGINLATAD 1149

  Fly   608 IIVFAELDWNPSTLAQAESRAHRIGQTKPVICRYLIAHNTADDIIWNMLKNKQEVL--------- 663
            .::..:.||||....||.||||||||.|.|:....:...:.::.|..:.|.|..:.
Zfish  1150 TVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTKASVEERITQVAKKKMMLTHLVVRPGLG 1214

  Fly   664 SKVG-----------------IFAENLQKATHTAAPTS-----SHKIEEYFSPSTSTSLEPERNS 706
            ||.|                 :|.:.|.:..:....:|     ...|:.....:...:.:.|..|
Zfish  1215 SKAGSMSKQELDDILKFGTEQLFKDELGEGDNKEEDSSVIHYDDKAIDRLLDRNQDATEDTELQS 1279

  Fly   707 IKQYFSTIP-----AKEPPEQNNNTEMTKVNKAES 736
            :.:|.|:..     .|:..|:..:.:...:.:.||
Zfish  1280 MNEYLSSFKVAQYVVKDEDEEEEDVDREIIKQEES 1314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	11/52 (21%)
		HepA	<233..666	CDD:440319	135/514 (26%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	63/242 (26%)
chd4b	XP_021322613.1	CHDNT	155..210	CDD:462357
		PHD1_CHD_II	377..419	CDD:277006
		PHD2_CHD_II	459..501	CDD:277007
		CD1_tandem_CHD3-4_like	506..584	CDD:349314
		CD2_tandem_CHD3-4_like	629..683	CDD:349309	9/33 (27%)
		PLN03142	734..>1274	CDD:215601	139/555 (25%)
		DEXHc_CHD4	736..967	CDD:350814	63/242 (26%)
		DUF1087	1308..1351	CDD:461922	2/7 (29%)
		CHDII_SANT-like	1397..1531	CDD:461920
		PTZ00121	<1534..>1738	CDD:173412
		CHDCT2	1769..1914	CDD:462358