Protein Alignment Marcal1 and chd5

DIOPT Version :10

• Sequence 1: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_073772935.1
• Gene: chd5 / 553422
• ZFINID: ZDB-GENE-120314-2
• Length: 2053
• Species: Danio rerio
• Alignment Length: 800
• Identity: 183/800 - (22%)
• Similarity: 299/800 - (37%)
• Gaps: 207/800 - (25%)

  Fly   115 PYQRPNGGNERNK-------PTLSLSSDK-----EKPVAVLLGNSITCNLYLISTHRFAAQTSGY 167
            ||...:|..|.|.       |..:...::     .||..::        ::.|..|.|  ...|.
Zfish   589 PYDYGSGEEELNNEKRRSKDPQYAAMEERFYRYGIKPEWLI--------IHRILNHSF--DKDGD 643

  Fly   168 HEQLVTVFKNMPTKCYDGQTRIW---SFDLSDYQSLKTHAADLKPYVHMNGI------------- 216
            .:.|:. ::::|   ||..:  |   .||:.||.|||....|     |.|.:
Zfish   644 VQYLIK-WRDLP---YDQCS--WEADDFDVPDYDSLKQAYWD-----HRNQVLGENHQPLLFRKG 697

  Fly   217 --PKKVLDLCGQPPVVP--ERSVLASIEPKLADQ----LMPFQQDG---VCFAIAQKGRIMICDE 270
              ||:.:.....||..|  :.::....:|...|.    |.|:|.:|   :.|:.||....::.||
Zfish   698 KRPKEEMKRREPPPDTPVVDPTIKFEQQPWYIDDTGGTLHPYQLEGLNWLRFSWAQGTDTILADE 762

  Fly   271 MGLGKTYQALA-VADYFKD---DWPLLVCTTASTRDSWAKHIMDLLPKVPIHYV----------Q 321
            ||||||.|.:. :...:|:   ..|.||....||..:|.:   :.....|..||          .
Zfish   763 MGLGKTVQTIVFLYSLYKEGHSKGPFLVSAPLSTIINWER---EFEMWAPDFYVVTYTGDKESRA 824

  Fly   322 VLNNNQLYVGEA-------------------KVLITSYNMMERHEDKLMQRKFGFIIFDESHTLK 367
            ::..|:....::                   .||:|||.::...:..|....:..::.||:|.||
Zfish   825 IIRENEFTFEDSAVKSGRKVFRMKKDTPIKFHVLLTSYELITIDQAILGSITWACLVVDEAHRLK 889

  Fly   368 NSKAKCTTTAKRLTDQAK--RVVLLSGTPALSRPLELFTQLQMIDGKFMNFMEFTTRYCDGKQST 430
            |:::|..    |:.:..|  ..:||:|||..:...|||..|..:..:..|.:|       |....
Zfish   890 NNQSKFF----RILNGYKIYYKLLLTGTPLQNNLEELFHLLNFLTPERFNNLE-------GFLEE 943

  Fly   431 FGWDANGQSNLEELKVILHLKYMLRRTKVEVLPQLAEKNRETVV---LDP------ALVWTNAET 486
            |. |.:.:..:::|..:|. .:||||.|.:|...:..|. |.:|   |.|      ..:.|.
Zfish   944 FA-DISKEDQIKKLHDLLG-PHMLRRLKADVFKNMPAKT-ELIVRVELSPMQKKYYKFILTR--- 1002

  Fly   487 KETLDAFNKELKTAKGRATEEILLRF----------------------------YARTAEVKTRA 523
                   |.|...:||...:..||..                            |.....||:..
Zfish  1003 -------NFEALNSKGGGNQVSLLNIMMDLKKCCNHPYLFPVAAVEAPVLPNGSYDGNLLVKSSG 1060

  Fly   524 VCAYLKTLVKEQK----KFIIFAHHRVMMDAISDFLSGLKVHYIRIDGQTRSDHRSDSVDTFQKK 584
            ....|:.::.:.|    :.:||:....|:|.:.|||......|.||||......|.:::|.|...
Zfish  1061 KLTLLQKMLIKLKDGGHRVLIFSQMTKMLDLLEDFLEFEGYKYERIDGGITGGLRQEAIDRFNAP 1125

  Fly   585 SSCKVA-LLSLKACNSGITLTAAEIIVFAELDWNPSTLAQAESRAHRIGQTKPVICRYLIAHNTA 648
            .:.:.. |||.:|...||.|..|:.::..:.||||....||.||||||||.|.|:....:...:.
Zfish  1126 GAQQFCFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASV 1190

  Fly   649 DDIIWNMLKNKQEVL---------SKVGIFA------------ENLQKATHTAAPTSSH-KIEEY 691
            ::.|..:.|.|..:.         ||.|..:            |.|.|....||.|... |:.|.
Zfish  1191 EERITQVAKRKMMLTHLVVRPGLGSKTGSMSKQELDDILKFGTEELFKDDVEAARTMGELKVLEM 1255

  Fly   692 FS---------------PSTSTSLEPERNSIKQYFSTIPAKEPPEQNNNTEMTKVNKAESDIAAF 741
            .|               .||..:.|.|..|:..|.....:|......:.||.|::......:::|
Zfish  1256 KSIVLPLCVPIAEVLNLSSTGDNKEGEEVSVIHYDDNAISKLLDRSQDATEDTEIQNMNEYLSSF 1320

  Fly   742 ------FNDDDDEAFLELDI 755
                  ..::|.|..::.:|
Zfish  1321 KVAQYVVREEDGEEEVQREI 1340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	17/58 (29%)
		HepA	<233..666	CDD:440319	126/525 (24%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	60/246 (24%)
chd5	XP_073772935.1	None