Protein Alignment Marcal1 and smarcad1

DIOPT Version :10

• Sequence 1: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001015697.1
• Gene: smarcad1 / 548414
• XenbaseID: XB-GENE-492700
• Length: 1003
• Species: Xenopus tropicalis
• Alignment Length: 760
• Identity: 193/760 - (25%)
• Similarity: 299/760 - (39%)
• Gaps: 193/760 - (25%)

  Fly    43 TGATQHA-----NNGK------SNPNQPQAKSPLNFYRSPTGEQKKINRSGPTPGDNKSSSFLNA 96
            |.|.|:|     :|||      .|.|:..||:..|...:....|..:.:.|  .|...|.   ||
 Frog   267 TDALQNAAKKEVSNGKEFSRSNKNDNKSSAKAKANQNSNKAMAQNGVKKKG--KGKKYSE---NA 326

  Fly    97 LKAIKQTSNRELSRGAAHPYQRP-NGGNERNKPTLSLSSDKEKPVAVLLGNSITCNLYLI--STH 158
            .:..:...:.|.:..|....... :.|:|:      |..:.:..:...|.::....||||  .:|
 Frog   327 KRDTRDLESEESASDAGSCLDEDYSSGDEK------LEEEYKTKILSFLQDASLDELYLIPHCSH 385

  Fly   159 RFAAQTSGYH--EQLVTVFKNMPTKCYDGQTRIWSFDLSDYQSL-KTHAADLKPYVHMN------ 214
            :.|.:.:...  ....::|:.|.......:..||     |.|:| |.....:|   .||
 Frog   386 KKAQKITELRPFSSWESLFEKMTKSNGLSEDLIW-----DCQTLIKEREVVMK---LMNKCEEIS 442

  Fly   215 -GIPKKVLDL-----CG----QPPVVPERSVLASIEPKLADQLMPFQQDGV-CFAIAQKGRI--M 266
             .:.|:|..|     ||    ||.::.|..|           |.|:|:.|: ..|:..|.::  :
 Frog   443 RTLTKQVTQLTEDGECGWNIEQPSIMSENLV-----------LKPYQKIGLNWLALLHKHKVNMI 496

  Fly   267 ICDEMGLGKTYQALAVADYF---KDDWPLLVCTTASTRDSWAKHIMDLLPKVPI--HY------- 319
            :.||||||||.||:|...:.   .|..|.||...|||.|:|.:......|.:.|  :|
 Frog   497 LADEMGLGKTVQAIAFLAHLYVTGDSGPHLVVVPASTMDNWIREFNQWCPSMNILLYYGSQEERK 561

  Fly   320 ---VQVLNNNQLYVGEAKVLITSYN-MMERHEDKLMQR--KFGFIIFDESHTLKNSKAKCTTTAK 378
               ..:||.    |.|..|::|:|| .:...||:.:.|  |..|.:|||.|.|||..|  .....
 Frog   562 HLRYDILNK----VVEFNVIVTTYNCAISSAEDRSLFRRLKLNFAVFDEGHMLKNMSA--IRYQH 620

  Fly   379 RLTDQAKRVVLLSGTPALSRPLELFTQLQMIDGKFMNFM------EFTTRYCDGKQSTFGWDANG 437
            .:|..|:..:||:|||..:..|||.:.|..:    |..|      |....:....:||      .
 Frog   621 LMTLNARSRLLLTGTPVQNNLLELMSLLNFV----MPHMFSSSTSEIKRLFSSKAKST------D 675

  Fly   438 QSNLEELKVILHLK-----YMLRRTKVEVLPQL-----------AEKNRETVVLDPALVWTNAET 486
            :..:.|.:.|.|.|     ::|||.|.|||.||           ..|.:|.:..|     ...:.
 Frog   676 EQTIFEKERIAHAKQIMKPFILRRVKSEVLKQLPPKQDKIKFCQMSKKQEQLYSD-----LLNKL 735

  Fly   487 KETLDAFNKE------LKTAKGRATEEILLRFYARTAEVKTRA---------------------- 523
            |:::||..|.      :...:..|...:|.|.|.....::|.:
 Frog   736 KKSIDATEKNSELCNVMMHLRKMANHPLLHRQYYTADRLRTMSKLMLKEPTHCDANPDLIFEDME 800

  Fly   524 ---------VCAYL---------KTLVKEQKKF-----------------IIFAHHRVMMDAISD 553
                     :|...         |.|:.:..||                 ::|:...:|:|.|..
 Frog   801 VMTDFELHRLCNEFTTLSQYKLEKELILDSGKFNILEKLLSDIKKKGDRVVLFSQFTMMLDIIEV 865

  Fly   554 FLSGLKVHYIRIDGQTRSDHRSDSVDTFQKKSSCKVALLSLKACNSGITLTAAEIIVFAELDWNP 618
            ||...:..|:|:||:|:...|...:|.|.......:.|||.||...||.||:|.|::..::|.||
 Frog   866 FLRHHQHRYVRLDGKTQISERIHLIDEFNTDMDIFIFLLSTKAGGLGINLTSANIVILHDIDCNP 930

  Fly   619 STLAQAESRAHRIGQTKPVICRYLIAHNTADDIIWNMLKNKQEVL 663
            ....|||.|.||:||||.|....||...|.::   :|||..|:.|
 Frog   931 YNDKQAEDRCHRVGQTKEVKVIKLIGKGTIEE---SMLKISQQKL 972

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	12/65 (18%)
		HepA	<233..666	CDD:440319	144/537 (27%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	71/240 (30%)
smarcad1	NP_001015697.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	15..130
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	172..235
		CUE	223..259	CDD:270465
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	274..351		16/81 (20%)
		HepA	<471..974	CDD:440319	144/537 (27%)
		DEGH box	605..608		2/2 (100%)