Protein Alignment Marcal1 and Chd3

DIOPT Version :10

• Sequence 1: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_649111.1
• Gene: Chd3 / 40111
• FlyBaseID: FBgn0023395
• Length: 892
• Species: Drosophila melanogaster
• Alignment Length: 727
• Identity: 160/727 - (22%)
• Similarity: 268/727 - (36%)
• Gaps: 202/727 - (27%)

  Fly   117 QRPNGGNERNKPTLSLSSDKEKPVAVLLGNSITCNLYLISTHRFAAQTSGYH---------EQLV 172
            :.||||                            .:||:.....:...|.:.         .|.:
  Fly   189 EEPNGG----------------------------TMYLVKWRELSYNDSSWERESDSIPGLNQAI 225

  Fly   173 TVFKNMPTKCYDGQTRIWSFDLSDYQSLKTHAADL-KPYVHMNGIPKKVLDLCGQPPVVPERSVL 236
            .::|.:.:                  |.|....|. .|.:.:|   ||..|   ||..:.|..:
  Fly   226 ALYKKLRS------------------SNKGRQRDRPAPTIDLN---KKYED---QPVFLKEAGL- 265

  Fly   237 ASIEPKLADQLMPFQQDGVCFAIAQKGR---IMICDEMGLGKTYQALA-VADYFKDD---WPLLV 294
                     :|.|||.:||.:.....|:   .::.||||||||.|.:. :...||:.   .|.|:
  Fly   266 ---------KLHPFQIEGVSWLRYSWGQGIPTILADEMGLGKTIQTVVFLYSLFKEGHCRGPFLI 321

  Fly   295 CTTASTRDSWAKHIMDLLPKV-PIHYV------QVLNNNQLYVGEA--------------KVLIT 338
            ....||..:|.:.:....|:: .:.||      .|:..:::...|.              .|::|
  Fly   322 SVPLSTLTNWERELELWAPELYCVTYVGGKTARAVIRKHEISFEEVTTKTMRENQTQYKFNVMLT 386

  Fly   339 SYNMMERHEDKLMQRKFGFIIFDESHTLKNSKAKCTTTAKRLTDQAKRVVLLSGTPALSRPLELF 403
            ||..:......|....:..::.||:|.|:::::|......:.....|  :||:|||..:...|||
  Fly   387 SYEFISVDAAFLGCIDWAALVVDEAHRLRSNQSKFFRILSKYRIGYK--LLLTGTPLQNNLEELF 449

  Fly   404 TQLQMI-DGKFMNFMEFTTRYCDGKQSTFGWDANGQSNLEELKVILHLKYMLRRTKVEVLPQLAE 467
            ..|..: .|||.:...|...:.         |.:.:..::.|..||. .:||||.|.:||..:..
  Fly   450 HLLNFLSSGKFNDLQTFQAEFT---------DVSKEEQVKRLHEILE-PHMLRRLKADVLKSMPP 504

  Fly   468 KNRETVVLDPALVWTNAETKETLDAFNKELKTAK---------GR-------------------- 503
            |: |.:|        ..|.......|.|.:.|..         ||
  Fly   505 KS-EFIV--------RVELSSMQKKFYKHILTKNFKALNQKGGGRVCSLLNIMMDLRKCCNHPYL 560

  Fly   504 ---ATEEILLR---FYARTAEVKTRAVCAYLKTLVKEQK----KFIIFAHHRVMMDAISDFLSGL 558
               |.||..:.   .|..::..|.......|..::|:.|    :.::|:....|::.:..||.|.
  Fly   561 FPSAAEEATISPSGLYEMSSLTKASGKLDLLSKMLKQLKADNHRVLLFSQMTKMLNVLEHFLEGE 625

  Fly   559 KVHYIRIDGQTRSDHRSDSVDTFQKK-SSCKVALLSLKACNSGITLTAAEIIVFAELDWNPSTLA 622
            ...|.||||..:.|.|..::|.|... |...|.|||.:|...||.|..|:.::..:.||||....
  Fly   626 GYQYDRIDGSIKGDLRQKAIDRFNDPVSEHFVFLLSTRAGGLGINLATADTVIIFDSDWNPHNDV 690

  Fly   623 QAESRAHRIGQTKPVICRYLIAHNTADDIIWNMLKNKQ-----------------------EVLS 664
            ||.|||||:||.|.|:....:.||:.::.|..:.|:|.                       |.:.
  Fly   691 QAFSRAHRMGQKKKVMIYRFVTHNSVEERIMQVAKHKMMLTHLVVRPGMGGMTTNFSKDELEDIL 755

  Fly   665 KVG---IFAENLQKATHTAAPTSSHKIEEYFSPSTSTSLEPERNSIKQYFSTI-----PAKEPPE 721
            :.|   :|.:...:|.|......:..::.     |:..:|.:.:...:|.|:.     ..||..|
  Fly   756 RFGTEDLFKDGKSEAIHYDDKAVADLLDR-----TNRGIEEKESWANEYLSSFKVASYATKEDHE 815

  Fly   722 Q----NNNTEMT 729
            :    ||:.|.|
  Fly   816 EHDDYNNDAENT 827

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	8/65 (12%)
		HepA	<233..666	CDD:440319	125/524 (24%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	58/237 (24%)
Chd3	NP_649111.1	PHD2_CHD_II	37..79	CDD:277007
		CD_CSD	82..146	CDD:475127
		CD2_tandem_CHD3-4_like	176..230	CDD:349309	8/68 (12%)
		PLN03142	266..>768	CDD:215601	127/522 (24%)