Protein Alignment Marcal1 and CG7376

DIOPT Version :10

• Sequence 1: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_648034.1
• Gene: CG7376 / 38715
• FlyBaseID: FBgn0035689
• Length: 1270
• Species: Drosophila melanogaster
• Alignment Length: 669
• Identity: 124/669 - (18%)
• Similarity: 230/669 - (34%)
• Gaps: 222/669 - (33%)

  Fly   123 NERNKPTLSLSSDKEKPVAVLLGNSITCNLYLIST-----HRFAAQTSGYHEQLVTVFKNMPTKC 182
            ||.|:..:|:.|       ||..::| .||...|:     |:.   |...|::.......:..|.
  Fly   667 NEYNEQNISVDS-------VLQIHAI-YNLLQASSLAPAEHKL---TELEHKKYQAQMSRLEWKY 720

  Fly   183 YDGQTRIWSFDLSDYQSLKTHAADLKPYVHMNGIPKKVLDLCGQPPVVPERSVLASIEPKLADQL 247
            .:..||:....||.|.......::|:.  ...|   ..|||.. ..|..:.|:..:|..|:.|..
  Fly   721 LEDNTRVLESALSSYNENLEKVSELEK--RFEG---STLDLLA-TMVNHKTSLHDAIWNKVRDDF 779

  Fly   248 MPFQQDGVCFAIAQKGRIMICDEMGLGKTYQALAVADYFKDDW---------PLL---------- 293
              |:|:   .::.:...:            .::|...||.|.|         .|:
  Fly   780 --FRQN---ISVERLENV------------NSMAGMLYFMDIWHNKLQNLKSTLIAEFEFLKGVM 827

  Fly   294 --VCTTASTRDSWAKHIMDLLPKVPI-HYVQVLNNNQLYVGEAKVLITSYNMMERHEDKLMQRKF 355
              .|....|....:..|::.:..|.: |...:|:.|                    :||.::.|
  Fly   828 QQACEAIKTGVLLSMEIINFIENVTVCHLTDILDAN--------------------KDKPVKPK- 871

  Fly   356 GFIIFDESH------TLKNS--KAKCTTTAKRLTDQAKRVVLLSGTPALSRP-LELFTQLQMIDG 411
                   .|      .:::|  :.:|...||:|.::|      :.|..|..| :|:
  Fly   872 -------KHRYCRLCLIRDSLNQFECLLFAKKLDEKA------TVTEGLENPSMEI--------- 914

  Fly   412 KFMNFMEFTTRYCDGKQSTFGWDANGQSNLE-----------ELKVILHLKYM------LRRTKV 459
               :|::....:...||....|....||.||           ::|..:.::||      |...|:
  Fly   915 ---SFIKSIFAFLRSKQDFSEWKEECQSKLELLSCLQDLVKFQIKYWIEVEYMVKAFDELEMCKM 976

  Fly   460 EVL----PQLAEKNRETVV---LDPALVWT--NAET------------------KETLDAFNK-- 495
            .:|    |:  |::...::   ||..|.:.  |.:|                  ||  |:.:|
  Fly   977 RILLTDDPE--EQSNYRILACQLDEQLQFNQYNLQTSQLNFTRLCGRLKYLKHLKE--DSADKPC 1037

  Fly   496 --------------------------ELKTAKGRA---------TEEILLRFYARTAEVK----- 520
                                      .::...|||         .:...|.:..|....|
  Fly  1038 PICQTQDDVRYVMMVCGHFVCQHCLDSMRRKNGRAGVTKCPLCRQDSPQLYYSVRPGAHKSIIGD 1102

  Fly   521 -TRAVCAYLKTLVK-----EQKKFIIFAHHRVMMDAISDFLSGLKVHYIRIDG-QTRSDHRSDSV 578
             :..:.:.::.::|     ||:|.|:|:..:.::..|:..||        ::| |.|:...:...
  Fly  1103 FSTKISSVVELVLKIKGENEQEKIIVFSQWQAILIEIARALS--------LNGIQFRNKCTNKDF 1159

  Fly   579 DTFQKK-SSCKVALLSLKACNSGITLTAAEIIVFAELDWNPSTLAQAESRAHRIGQTKPVICRYL 642
            |.|:.. |:....|:.|...:.|:.|..|..:...|...||....||..|.||.||.:|......
  Fly  1160 DDFKNPLSNVTCLLMPLSKGSKGLNLIEATHVFLVEPILNPGDERQAIGRIHRFGQKRPTKVHRF 1224

  Fly   643 IAHNTADDIIWNMLKNKQE 661
            |.:.|.::.|.:::.:..:
  Fly  1225 IVNETIEENILSLITSADD 1243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	9/55 (16%)
		HepA	<233..666	CDD:440319	98/554 (18%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	41/256 (16%)
CG7376	NP_648034.1	DEXQc_SHPRH	160..513	CDD:350828
		PHD_SF	281..320	CDD:473978
		TPR	636..669	CDD:197478	1/1 (100%)
		RING_Ubox	1036..1082	CDD:473075	3/45 (7%)
		SF2_C_SNF	1104..1225	CDD:350180	31/128 (24%)