Protein Alignment Marcal1 and Smarca1

DIOPT Version :10

• Sequence 1: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001258119.1
• Gene: Smarca1 / 317575
• RGDID: 1561046
• Length: 1062
• Species: Rattus norvegicus
• Alignment Length: 808
• Identity: 184/808 - (22%)
• Similarity: 306/808 - (37%)
• Gaps: 193/808 - (23%)

  Fly    38 STTSATGATQHANNGKSNPNQPQAKSPLNFYRS-----PTGEQKKINRSGPTPGDN-KSSSFLNA 96
            :.|.||.||:.....:...:..|.|......:|     |..|:|.:|.  |...|. |...||
  Rat    42 AATEATTATEKGEKKEKITSPFQLKLAAKTSKSEKEMDPEYEEKMVNI--PLKADRAKRFEFL-- 102

  Fly    97 LKAIKQTSNRELSRGAAHPYQRPNGGNERNKPTLSLSSDKEKPVAVLLGNSITCNLYLISTHRFA 161
               :|||   ||   .|| :.:|:.   :..||..|:....:|
  Rat   103 ---LKQT---EL---FAH-FIQPSA---QKSPTSPLNMKLARP---------------------- 132

  Fly   162 AQTSGYHEQLVTVFKNMPTKCYDGQTRIWSFDLSDYQSLKTHAADLKPYVHMNGIPKKVLDLCGQ 226
                             ..|..|.|:.|   .:.||:..:|...:.:..:..:   :|..::|.:
  Rat   133 -----------------RVKKDDKQSLI---SVGDYRHRRTEQEEDEELLSES---RKTSNVCVR 174

  Fly   227 PPVVP---ERSVLASIEPKLADQLMPFQQDGVCFAIAQKGRIMICDEMGLGKTYQALAVADYFKD 288
            ..|.|   :...|...:.:..:.|:...::||      .|  ::.||||||||.|.:|:..|.|.
  Rat   175 FEVSPSYVKGGPLRDYQIRGLNWLISLYENGV------NG--ILADEMGLGKTLQTIALLGYLKH 231

  Fly   289 ----DWPLLVCTTASTRDSWAKHIMDLLPKV-PIHYV------QVLNNNQLYVGEAKVLITSYNM 342
                ..|.:|....||..:|.......:|.: .|.:|      .....:::..||..|.:|||.|
  Rat   232 YRNFPGPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDVRAAFIRDEMMPGEWDVCVTSYEM 296

  Fly   343 MERHEDKLMQRKFGFIIFDESHTLKNSKAKCTTTAKRLTDQAKRVVLLSGTPALSRPLELFTQLQ 407
            :.:.:....:..:.:::.||:|.:||.|:|.:...:..  ::...:||:|||..:...||:..|.
  Rat   297 VIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREF--KSTNRLLLTGTPLQNNLHELWALLN 359

  Fly   408 MIDGKFMNFME-----FTTRYCDGKQSTFGWDANGQSNLEELKVILHLKYMLRRTKVEVLPQLAE 467
            .:.....|..:     |.|:.|.|.|..          :|.|..:|. .::|||.|.:|...|..
  Rat   360 FLLPDVFNSADDFDSWFDTKNCLGDQKL----------VERLHAVLK-PFLLRRIKTDVEKSLPP 413

  Fly   468 KNRETVVLDPALV---WTNAETKETLDAFNKELKTAKGRATEEILLRF----------------- 512
            |....:.|..:.:   |......:.:|..|...|..|.|.. .||::.
  Rat   414 KKEIKIYLGLSKMQREWYTKILMKDIDVLNSSGKMDKMRLL-NILMQLRKCCNHPYLFDGAEPGP 477

  Fly   513 -YARTAEVKTRA--VCAYLKTL--VKEQ-KKFIIFAHHRVMMDAISDFLSGLKVHYIRIDGQTRS 571
             |.....:.:.:  :.|..|.|  :||| .:.:||:....::|.:.|:.......|.|:||||..
  Rat   478 PYTTDEHIVSNSGKMVALDKLLARIKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQTPH 542

  Fly   572 DHRSDSVDTFQKKSSCK-VALLSLKACNSGITLTAAEIIVFAELDWNPSTLAQAESRAHRIGQTK 635
            :.|.::::.|...:|.| :.:||.:|...||.|.:|::::..:.||||....||..|||||||.|
  Rat   543 EEREEAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQVDLQAMDRAHRIGQKK 607

  Fly   636 PVICRYLIAHNTADDII-----------------WNMLKNKQEVLSKVGIFAENLQKATHTAAPT 683
            ||....||..||.::.|                 ..::..:...|:|..:.......|||..|..
  Rat   608 PVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQSNKLAKEEMLQMIRHGATHVFACK 672

  Fly   684 SSHKIEE-----------------------------YFSPSTSTSL---EPERNSIKQYFSTIPA 716
            .|...:|                             .|......||   |.|....||...|:..
  Rat   673 ESELTDEDIVTILERGEKKTAEMNERMQKMGESSLRNFRMDLEQSLYKFEGEDYREKQKLGTVEW 737

  Fly   717 KEPPEQNNNTEMTKVNKAESDIAAFFND 744
            .|||::.        .||...:.|:|.:
  Rat   738 IEPPKRE--------RKANYAVDAYFRE 757

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	7/55 (13%)
		HepA	<233..666	CDD:440319	122/492 (25%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	56/224 (25%)
Smarca1	NP_001258119.1	PLN03142	64..1061	CDD:215601	179/786 (23%)