Protein Alignment Marcal1 and Smarca5

DIOPT Version :10

• Sequence 1: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001424549.1
• Gene: Smarca5 / 307766
• RGDID: 1308832
• Length: 1072
• Species: Rattus norvegicus
• Alignment Length: 825
• Identity: 191/825 - (23%)
• Similarity: 308/825 - (37%)
• Gaps: 199/825 - (24%)

  Fly    32 PATNGKSTTSATGATQHANNGKSNPN---QPQAKSPLN-----------FYRSPTGEQKKINRSG 82
            |..:..|..||.||...::..|..|.   .|.|.|...           |.....|:||:|....
  Rat    12 PPESAPSKPSAAGAGGSSSGNKGGPEGGAAPAAPSATGAGPADTEMEEVFDDGSPGKQKEIQEPD 76

  Fly    83 PTPGDNKSSSFLNALK-AIKQTSNRELSRGAAHPYQRPNGGNERNKPTLSLSSDKEKPVAVLLGN 146
            ||..:...:...|..: .:|||   ||   .|| :.:|..   :..||..|   |.||....:..
  Rat    77 PTYEEKMQTDRANRFEYLLKQT---EL---FAH-FIQPAA---QKTPTSPL---KMKPGRPRVKK 128

  Fly   147 SITCNLYLISTHRFAAQTSGYHEQLVTVFK---NMPTKCYDGQTRIWSFDLSDYQSLKTHAADLK 208
            ....||..:..:|.........|:|:|...   |:.|:..|..:.:....|.|||
  Rat   129 DEKQNLLSVGDYRHRRTEQEEDEELLTESSKATNVCTRFEDSPSYVKWGKLRDYQ---------- 183

  Fly   209 PYVHMNGIPKKVLDLCGQPPVVPERSVLASIEPKLADQLMPFQQDGVCFAIAQKGRIMICDEMGL 273
                :.|:                            :.|:...::|:      .|  ::.|||||
  Rat   184 ----VRGL----------------------------NWLISLYENGI------NG--ILADEMGL 208

  Fly   274 GKTYQALAVADYFKD----DWPLLVCTTASTRDSWAKHIMDLLPKVPIHYVQVLNNNQ------- 327
            |||.|.:::..|.|.    ..|.:|....||..:|.......:|  .:..|.::.:.:
  Rat   209 GKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKRWVP--TLRSVCLIGDKEQRAAFVR 271

  Fly   328 --LYVGEAKVLITSYNMMERHEDKLMQRKFGFIIFDESHTLKNSKAKCTTTAKRLTDQAKRVVLL 390
              |..||..|.:|||.|:.:.:....:..:.:::.||:|.:||.|:|.:...:..  :....:||
  Rat   272 DVLLPGEWDVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREF--KTTNRLLL 334

  Fly   391 SGTPALSRPLELFTQLQMIDGKFMNFME-----FTTRYCDGKQSTFGWDANGQSNLEELKVILHL 450
            :|||..:...||::.|..:.....|..:     |.|..|.|.|..          :|.|.::|.
  Rat   335 TGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQKL----------VERLHMVLR- 388

  Fly   451 KYMLRRTKVEVLPQLAEKNRETVVLDPALV---WTNAETKETLDAFNKELKTAKGRATEEILLRF 512
            .::|||.|.:|...|..|....:.:..:.:   |......:.:|..|...|..|.|.. .||::.
  Rat   389 PFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAGKMDKMRLL-NILMQL 452

  Fly   513 ------------------YARTAEVKTRA----VCAYLKTLVKEQ-KKFIIFAHHRVMMDAISDF 554
                              |.....:.|.:    |...|...:||| .:.:||:....::|.:.|:
  Rat   453 RKCCNHPYLFDGAEPGPPYTTDMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDY 517

  Fly   555 LSGLKVHYIRIDGQTRSDHRSDSVDTFQKKSSCK-VALLSLKACNSGITLTAAEIIVFAELDWNP 618
            .......|.|:||||..|.|.||::.:.:.:|.| |.:||.:|...||.|..|::::..:.||||
  Rat   518 CMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNP 582

  Fly   619 STLAQAESRAHRIGQTKPVICRYLIAHNTADDIIWNMLKNKQE----VLSKVGIFAENLQK---- 675
            ....||..|||||||||.|.....|..||.::.|....:.|..    |:.:..:..:||.|
  Rat   583 QVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGRLVDQNLNKIGKD 647

  Fly   676 ---------ATHTAAPTSSHKIEE-----------------------------YFSPSTSTSL-- 700
                     |||..|...|...:|                             .|:..|.:|:
  Rat   648 EMLQMIRHGATHVFASKESEITDEDIDGILERGAKKTAEMNEKLSKMGESSLRNFTMDTESSVYN 712

  Fly   701 -EPERNSIKQYFSTIPAKEPPEQNNNTEMTKVNKAESDIAAFFND 744
             |.|....||..:.....|||::.        .||...:.|:|.:
  Rat   713 FEGEDYREKQKIAFTEWIEPPKRE--------RKANYAVDAYFRE 749

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	10/58 (17%)
		HepA	<233..666	CDD:440319	121/481 (25%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	54/226 (24%)
Smarca5	NP_001424549.1	None