Protein Alignment Marcal1 and smarca5

DIOPT Version :10

• Sequence 1: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001075098.2
• Gene: smarca5 / 282615
• ZFINID: ZDB-GENE-021125-1
• Length: 1035
• Species: Danio rerio
• Alignment Length: 953
• Identity: 203/953 - (21%)
• Similarity: 324/953 - (33%)
• Gaps: 344/953 - (36%)

  Fly     1 MSTCSSSEIAEKKRIALAKLQAKKSQLLASAPA-----TNGKSTTSATGATQHANNGKSNPNQPQ 60
            ||...||  .|::|      :.:.|||..:.||     .||....|.|.....|.:  |:|...:
Zfish     1 MSQTESS--MEQQR------EEEPSQLDPAGPAEDDTSENGHDEASDTAMDSEAQS--SSPPSAK 55

  Fly    61 AKSPLNFYRSPTGEQKKINRSGPTPGDNKSSSFLNALK-----------AIKQTSNRELSRGAAH 114
            .|..|.      |.::|:.       .::::.|...||           |.::|....|......
Zfish    56 GKDLLG------GYEEKVQ-------TDRTNRFEYLLKQTEVFAHFIQPAAQKTPTSPLKMKPGR 107

  Fly   115 PY----QRPN---GGNERNKPTLSLSSDKEKPVAVLLGNSITCNLYLISTHRFAAQTSGYHEQLV 172
            |.    ::.|   .|:.|::.|     ::|:...:|..||              ..||     :.
Zfish   108 PRIKKDEKQNLLSAGDNRHRRT-----EQEEDEELLSENS--------------KATS-----VC 148

  Fly   173 TVFKNMPTKCYDGQTRIWSFDLSDYQSLKTHAADLKPYVHMNGIPKKVLDLCGQPPVVPERSVLA 237
            |.|.:.|:....|:.|       |||              :.|:
Zfish   149 TRFDDSPSYVKTGKLR-------DYQ--------------VRGL--------------------- 171

  Fly   238 SIEPKLADQLMPFQQDGVCFAIAQKGRIMICDEMGLGKTYQALAVADYFKD----DWPLLVCTTA 298
                   :.|:...::|:      .|  ::.||||||||.|.:::..|.|.    ..|.:|....
Zfish   172 -------NWLISLYENGI------NG--ILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPK 221

  Fly   299 STRDSWAKHIMDLLPKVPIHYVQVLNNNQ---------LYVGEAKVLITSYNMM--ERHEDKLMQ 352
            ||..:|.......:|.  :..|.::.:.:         |..||..|.:|||.|:  ||    .:.
Zfish   222 STLYNWMNEFKRWVPS--LKAVCLIGDREERTAFIRDTLLPGEWDVCVTSYEMLIIER----AVF 280

  Fly   353 RKFG--FIIFDESHTLKNSKAKCTTTAKRLTDQAKRVVLLSGTPALSRPLELFTQLQMIDGKFMN 415
            :||.  :::.||:|.:||.|:|.:...:..  :....:||:|||..:...||:..|..:.....|
Zfish   281 KKFNWRYLVIDEAHRIKNEKSKLSEIVREF--KTTNRLLLTGTPLQNNLHELWALLNFLLPDVFN 343

  Fly   416 FME-----FTTRYCDGKQSTFGWDANGQSNLEELKVILHLKYMLRRTKVEV----LPQ------- 464
            ..|     |.|..|.|....          :|.|..:|. .::|||.|.:|    ||:
Zfish   344 SSEDFDAWFDTNNCLGDTKL----------VERLHTVLR-PFLLRRIKADVEKSLLPKKEIKIYV 397

  Fly   465 -LAEKNRETVVLDPALVWTNAETKETLDAFNKELKTAKGRATEEIL------------------- 509
             |::..||         |......:.:|..|...|..|.|....::
Zfish   398 GLSKMQRE---------WYTKILMKDIDILNSAGKMDKMRLLNVLMQLRKCCNHPYLFDGAEPGP 453

  Fly   510 -----LRFYARTAEVKTRAVCAYLKTLVKEQ-KKFIIFAHHRVMMDAISDFLSGLKVHYIRIDGQ 568
                 |.....:.::   .|...|...:||| .:.:||:....::|.:.|:.......|.|:|||
Zfish   454 PYTTDLHLVVNSGKM---VVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYCMWRNYGYCRLDGQ 515

  Fly   569 TRSDHRSDSVDTFQKKSSCK-VALLSLKACNSGITLTAAEIIVFAELDWNPSTLAQAESRAHRIG 632
            |..:.|..|::.|.:.:|.| :.:||.:|...||.|..|::::..:.||||....||..||||||
Zfish   516 TPHEERQISINAFNEPNSSKFLFMLSTRAGGLGINLATADVVIIYDSDWNPQVDLQAMDRAHRIG 580

  Fly   633 QTKPVICRYLIAHNTADDII------------------------WNMLKNKQEVLSKV------- 666
            |.|.|.....|..||.::.|                        .|.| .|.|:||.:
Zfish   581 QKKQVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGRLVDPSMNKL-GKDEMLSIIRHGATHV 644

  Fly   667 --------------GI------------------------------------------------- 668
                          ||
Zfish   645 FASKESEITDEDIDGILERGERKTMEMKEKMANLGEGSLRNFTMDTENSVYNFEGEDYREKKKVV 709

  Fly   669 --------------------FAENLQ----KATHTAAPTSSHKIE--EYFSPSTSTSLEPERNSI 707
                                |.|.|:    ||.....|.....::  ::|.|.....||.|   |
Zfish   710 TNWIEPPKRERKANYAVDAYFREALRVSEPKAPKAPRPPKQPNVQDFQFFPPRLFELLEKE---I 771

  Fly   708 KQYFSTIPAKEP--PEQNNNTEMTKVNKAESDIAAFFNDDDDE 748
            ..|..||..|.|  |:..|:.||.|..:|:.|.|...|:::.|
Zfish   772 LYYRKTIGYKVPRNPDLPNSAEMQKEEQAKIDEAEPLNEEELE 814

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	10/55 (18%)
		HepA	<233..666	CDD:440319	126/516 (24%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	58/230 (25%)
smarca5	NP_001075098.2	PLN03142	4..1030	CDD:215601	201/950 (21%)