Protein Alignment Marcal1 and pqn-15

DIOPT Version :10

• Sequence 1: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_001367558.1
• Gene: pqn-15 / 180705
• WormBaseID: WBGene00004106
• Length: 2171
• Species: Caenorhabditis elegans
• Alignment Length: 731
• Identity: 175/731 - (23%)
• Similarity: 292/731 - (39%)
• Gaps: 132/731 - (18%)

  Fly    98 KAIKQTSNRELSRGAAHPYQRPNGGNERNKPTLSLSSDKEKPVAVLLGNSITCNLYLISTHRFAA 162
            |:::|....|..|.|     |....||:|:....:..|:|...|:|........:||:.
 Worm  1053 KSMQQYITNENKRIA-----REEMKNEKNRIQKLIQEDEEGYRAMLDEKKDQRLVYLLE------ 1106

  Fly   163 QTSGYHEQLVTVFK--------NMPTKC-----YDG---QTRIWSF------DLSDYQS-LKTHA 204
            ||..|.:.|..:.|        ::.||.     |||   :.::.|.      |..:|:: .|.:.
 Worm  1107 QTDDYIKSLCDLLKQQQNATAGSLATKSYIRKEYDGVAEEDKVKSILDKARNDDDEYENKTKMNI 1171

  Fly   205 ADLKPYVHMNGIPKKVLDLCGQPPVVPERSVLASIEPKLADQLMPFQQDGVCFAIAQKGRIM--- 266
            .|.  |...:|:.:::.:         :..::....|.|  :|.|:|..|:.:.::.....:
 Worm  1172 EDY--YTTAHGVREEIKE---------QHFMMGGGNPSL--KLKPYQIKGLEWMVSLFNNNLNGI 1223

  Fly   267 ICDEMGLGKTYQALAVADYF----KDDWPLLVCTTAST-------RDSWAKHIMDLLPKVPIHYV 320
            :.||||||||.|.:|...|.    |...|.||....||       .|.||.::..:..|.|....
 Worm  1224 LADEMGLGKTIQTIAFITYLMEIKKTSGPFLVIVPLSTVPNWQNEFDKWAANVHLIAYKGPKETR 1288

  Fly   321 QVLNNNQLYVGEAKVLITSYNMMERHEDKLMQRKFGFIIFDESHTLKNSKAKCTTTAKRLTDQAK 385
            :|. ...:..|:..||:|::..:.|.:..|.:.::.::|.||.|.|||...|.|... ....|.:
 Worm  1289 KVF-EPIIKSGKFNVLLTTFEYVIREKALLGKLRWKYMIIDEGHRLKNQHCKLTEML-NTRFQCQ 1351

  Fly   386 RVVLLSGTPALSRPLELFTQLQMIDGKFMNFMEFTTRYCDGKQSTFGWDANGQSNLEELKVI--- 447
            |.:|::|||..::..||:..|..:.....:......::.:...:|.|  ...:...||..:|
 Worm  1352 RRLLITGTPLQNKLPELWALLNFLLPSIFSSCSTFEQWFNAPFATTG--EKVELTQEETMLIIRR 1414

  Fly   448 LH---LKYMLRRTKVEVLPQLAEKNRETVVLDPA----LVWTNAETKETLDAFNKELKTAKGRAT 505
            ||   ..::|||.|.||..:|.:|....|..|.:    :::.:.:....||.     ||..|..:
 Worm  1415 LHKVLRPFLLRRLKKEVESELPDKMEFVVRCDMSALQKVLYKHMQKGLLLDG-----KTNTGSKS 1474

  Fly   506 ---------------------EEILLRFY-ARTAEV--------KTRAVCAYLKTLVKEQKKFII 540
                                 ||....|: ||....        |...:...|..|.....:.::
 Worm  1475 LRNTMIHLRKLCNHPFLFENVEESCRNFWDARFISAVDLYRVSGKLELLSRILPKLQATGHRVLM 1539

  Fly   541 FAHHRVMMDAISDFLSGLKVHYIRIDGQTRSDHRSDSVDTFQ-KKSSCKVALLSLKACNSGITLT 604
            |.....||..:.|||:|..:.|:|:||.|:.|.|...:|.|. ..|...:.:||.:|...|:.|.
 Worm  1540 FFQMTSMMTIVEDFLAGGTIQYLRLDGSTKPDERGALLDKFNAPNSEYFLFMLSTRAGGLGLNLQ 1604

  Fly   605 AAEIIVFAELDWNPSTLAQAESRAHRIGQTKPVICRYLIAHNTADDIIWNMLKNKQEVLSKVGIF 669
            .|:.::..:.||||....||:.|||||||...|....||..|:.::.|....:.|..|..||
 Worm  1605 TADTVIIFDSDWNPHQDMQAQDRAHRIGQKAEVRVFRLITANSVEEKILAAARYKLNVDEKV--- 1666

  Fly   670 AENLQKATHTAAPTSSHKIEEYFSPSTSTSLEPERNSIKQYFSTIPAKEPPEQNNNTEMTKVNKA 734
               :|........|.:.:.|         .||   |.||   :...::|..|..|:.::..:...
 Worm  1667 ---IQAGKFDNRSTGAERRE---------ILE---NIIK---TENESEEDEEVPNDEDINDILSR 1713

  Fly   735 ESDIAAFFNDDDDEAF 750
            ..:....|...|.|.|
 Worm  1714 SEEEFELFQKMDQERF 1729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	16/78 (21%)
		HepA	<233..666	CDD:440319	126/487 (26%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	59/228 (26%)
pqn-15	NP_001367558.1	Med15	<1..>288	CDD:312941
		Med15	<372..>592	CDD:312941
		HSA	1011..1083	CDD:214727	9/34 (26%)
		PLN03142	1062..>1726	CDD:215601	170/717 (24%)
		SnAC	1727..1799	CDD:464219	2/3 (67%)