Protein Alignment Marcal1 and smrc-1

DIOPT Version :10

• Sequence 1: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: NP_741192.1
• Gene: smrc-1 / 175907
• WormBaseID: WBGene00015806
• Length: 690
• Species: Caenorhabditis elegans
• Alignment Length: 733
• Identity: 242/733 - (33%)
• Similarity: 383/733 - (52%)
• Gaps: 97/733 - (13%)

  Fly     9 IAEKKRIALAKLQAKKSQLLASAPATNGKSTTSATGATQHANNGKSNPNQPQAKSPLNFYRSPTG 73
            :.:::|.|:||   |:.:.:..|.|...:...:|..||. :.:..:.|..|:...|:.|.::
 Worm     3 LTDEQRQAIAK---KREEAIRRAAAYREREMQAAANATA-STSSAAPPAPPKPVIPVMFSQN--- 60

  Fly    74 EQKKINRSGPTPGDN-KSSSFLNALKAIKQTSNRELSRGAAHPYQRPNGGNERNKPTLSLSSDKE 137
             ::......||..:: |.|:..|.:|.:::.....|.                 |||:.:.
 Worm    61 -RQNFQPMKPTMNNSTKQSTINNYIKQVQKPEPTSLI-----------------KPTIGVK---- 103

  Fly   138 KPVAVLLGNSITCNLYLISTHRFAAQTSGYHEQLVTVFKNMPTKCYDGQTRIWSFDLSDY---QS 199
              :.:.:|:.|....|            .:|..::.:.|.:|::.||...|.|:...||:   .:
 Worm   104 --LKLDIGDRIKIEFY------------PFHSAVIDLIKQVPSRNYDPAKRSWTVASSDHITISN 154

  Fly   200 LKTHAADLKPYVHMNGIPKKVLDLCGQPPVVPERSVLASIEPKLADQLMPFQQDGVCFAIAQKGR 264
            :..:|..:|  |.:..:|:.::.|....|......:...::|.|.::|.|:|::||.||:.:.||
 Worm   155 ILKNATAVK--VELEPLPQNIIGLTNFKPKAAPSDLNTVMDPSLIERLFPYQKEGVIFALERDGR 217

  Fly   265 IMICDEMGLGKTYQALAVADYFKDDWPLLVCTTASTRDSWAKHIMDLLPKVPIHYVQVLNNNQLY 329
            |::.|||||||:.|||.:|.|:|.|||||:...||.:.:|.|.:....|  .||.:.:::.:...
 Worm   218 ILLADEMGLGKSVQALTIARYYKADWPLLIVCPASVKGAWKKQLNTFFP--IIHRIFIVDKSSDP 280

  Fly   330 VGEA----KVLITSYNMMERHEDKLMQRKFGFIIFDESHTLKNSKAKCTTTAKRLTDQAKRVVLL 390
            :.:.    .|.|.||..|....|.|.:.|:..|||||||.||:.||:.|..|..|:..|..|:||
 Worm   281 LPDVCTSNTVAIMSYEQMVLKHDILKKEKYRTIIFDESHMLKDGKARRTKVATDLSKVALHVILL 345

  Fly   391 SGTPALSRPLELFTQLQMIDGK-FMNFMEFTTRYCDGKQSTFGWDANGQSNLEELKVILHLKYML 454
            |||||||||.|||||:::||.| |.||.||..|||||||..|.::|.|.:|.|||..|:..:.|:
 Worm   346 SGTPALSRPSELFTQIRLIDHKLFTNFHEFAIRYCDGKQGRFCFEAKGCTNSEELAAIMFKRLMI 410

  Fly   455 RRTKVEVLPQLAEKNRETVVLDPALVWTNAETKETLDAFNKELKTAKG--------RATEEILLR 511
            ||.|.:||..|.||.||.|.:          :..|:||...:|:.|:.        ....|.||.
 Worm   411 RRLKADVLKDLPEKRREVVYV----------SGPTIDARMDDLQKARADYEKVNSMERKHESLLE 465

  Fly   512 FYARTAEVKTRAVCAYLKTLVKEQ--------KKFIIFAHHRVMMDAISDFLSGLKVHYIRIDGQ 568
            ||:.|..||..|||.:    :.|.        :|.:|||||::::|.|...::..|:..|||||:
 Worm   466 FYSLTGIVKAAAVCEH----ILENYFYPDAPPRKVLIFAHHQIVLDTIQVEVNKRKLGSIRIDGK 526

  Fly   569 TRSDHRSDSVDTFQKKSSCKVALLSLKACNSGITLTAAEIIVFAELDWNPSTLAQAESRAHRIGQ 633
            |.|..|:...|:||...:.:||:||:.|...|||||||.::||||:.:||..|.|||.||||:||
 Worm   527 TPSHRRTALCDSFQTDDNIRVAVLSITAAGVGITLTAASVVVFAEIHFNPGYLVQAEDRAHRVGQ 591

  Fly   634 TKPVICRYLIAHNTADDIIWNMLKNKQEVLSKVGIFAENLQKA-------THTAAPTSSHKIEEY 691
            ...|..:||||..||||::|||::.|.:||.:|.:.::..:.|       ...|.|    .|.||
 Worm   592 KDSVFVQYLIAKKTADDVMWNMVQQKLDVLGQVSLSSDTFRTADKMHLRFNDAAQP----GIAEY 652

  Fly   692 FSPSTSTSLEPERNSIKQ 709
            ...:..|:::...:.:::
 Worm   653 LKKTPDTTIDEWEDPVEE 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	12/58 (21%)
		HepA	<233..666	CDD:440319	192/453 (42%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	99/213 (46%)
smrc-1	NP_741192.1	HARP	118..169	CDD:462166	12/52 (23%)
		DEXHc_HARP_SMARCAL1	200..412	CDD:350768	99/213 (46%)
		SF2_C_SNF	474..601	CDD:350180	55/130 (42%)