Protein Alignment Marcal1 and Smarca4

DIOPT Version :10

• Sequence 1: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_063120900.1
• Gene: Smarca4 / 171379
• RGDID: 621728
• Length: 1650
• Species: Rattus norvegicus
• Alignment Length: 897
• Identity: 191/897 - (21%)
• Similarity: 324/897 - (36%)
• Gaps: 260/897 - (28%)

  Fly    61 AKSPLNFYRSPTGEQKKINRSGPTPGDNKSSSFLNALKAIKQTSNRELSRGAAHPYQRPNGGNER 125
            ||....::||.||:.:|:.::..|...|.........:.|::...|.|.......|::
  Rat   483 AKDFREYHRSVTGKLQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK------- 540

  Fly   126 NKPTLSLSSDKEKPVAVLL--GNSITCNL-YLISTHRFAAQTSGYHEQLVTVFKNMPTKCYDGQT 187
                 .:...|:|.:|.||  .:....|| .|:..|: |||.:   ::.....|....:..:|||
  Rat   541 -----LIDQKKDKRLAYLLQQTDEYVANLTELVRQHK-AAQVA---KEKKKKKKKKKAENAEGQT 596

  Fly   188 RIWSFD---------LSDYQSLKTH--------------AADLKPYVHMNG----IPKKVLDLCG 225
            .....|         :||......|              |..|:.::.||.    .|:...:..|
  Rat   597 PAIGPDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEESG 661

  Fly   226 ----------------QPPVVP-------------------ERSVLASIEPKLADQLMPFQQDGV 255
                            |||.:|                   .|.::.:.:..:.|:.      ||
  Rat   662 SEEEEEEEEEEQPQPAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEY------GV 720

  Fly   256 CFAIAQ---------------------------------KG------------RIMICDEMGLGK 275
            ..|:|:                                 ||            ..::.|||||||
  Rat   721 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADEMGLGK 785

  Fly   276 TYQALAVADYFKD----DWPLLVCTTASTRDSWAKHIMDLLPKVPIHYVQVLNNN---------- 326
            |.|.:|:..|..:    :.|.|:....||..:||.......|.|    |:|....
  Rat   786 TIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSV----VKVSYKGSPAARRAFVP 846

  Fly   327 QLYVGEAKVLITSYNMMERHEDKLMQRKFGFIIFDESHTLKNSKAKCTTTAKRLTDQ-AKRVVLL 390
            ||..|:..||:|:|..:.:.:..|.:.::.::|.||.|.:||...|.|....  |.. |.|.:||
  Rat   847 QLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLN--THYVAPRRLLL 909

  Fly   391 SGTPALSRPLELFTQLQMIDGKFMNFMEFTT-RYCDGKQSTFG--WDANGQS-NLEELKVILHLK 451
            :|||..::..||:.        .:||:..|. :.|...:..|.  :...|:. :|.|.:.||.::
  Rat   910 TGTPLQNKLPELWA--------LLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIR 966

  Fly   452 --------YMLRRTKVEVLPQLAEKNRETVVLDPA----LVWTNAETKETLDAFNKELKTAKGRA 504
                    ::|||.|.||..||.||....:..|.:    :::.:.:.|..|.....| |..||:.
  Rat   967 RLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSE-KDKKGKG 1030

  Fly   505 TEEILLRFYARTAEVKTRAVCAY----------------------------------------LK 529
            ..:.|:     ...::.|.:|.:                                        |.
  Rat  1031 GTKTLM-----NTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILP 1090

  Fly   530 TLVKEQKKFIIFAHHRVMMDAISDFLSGLKVHYIRIDGQTRSDHRSDSVDTFQKK-SSCKVALLS 593
            .|.....|.::|.....:|..:.|:.:.....|:|:||.|:::.|...:.||.:. |...:.|||
  Rat  1091 KLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLS 1155

  Fly   594 LKACNSGITLTAAEIIVFAELDWNPSTLAQAESRAHRIGQTKPVICRYLIAHNTADDIIWNMLKN 658
            .:|...|:.|.:|:.::..:.||||....||:.|||||||...|....|...|:.::.|....|.
  Rat  1156 TRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKY 1220

  Fly   659 KQEVLSKV---GIFAENLQKATHTAAPTSSHKIEEYFSPSTSTSLEPERNSIKQYFST------I 714
            |..|..||   |:|.:.          :|||:...:.    ...||.|.....::.||      .
  Rat  1221 KLNVDQKVIQAGMFDQK----------SSSHERRAFL----QAILEHEEQDESRHCSTGSGSASF 1271

  Fly   715 PAKEPPEQNNNTEMTKVNKAESD-----------IAAFFNDDDDEAFLELDI 755
            ....||....|.::.:....|.|           ||.  ::::.:.|:.:|:
  Rat  1272 AHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIAR--HEEEFDLFMRMDL 1321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	15/82 (18%)
		HepA	<233..666	CDD:440319	127/549 (23%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	64/280 (23%)
Smarca4	XP_063120900.1	None