Protein Alignment Marcal1 and Chd1

DIOPT Version :10

• Sequence 1: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_061511441.1
• Gene: Chd1 / 1275545
• VectorBaseID: AGAMI1_005565
• Length: 2246
• Species: Anopheles gambiae
• Alignment Length: 832
• Identity: 167/832 - (20%)
• Similarity: 292/832 - (35%)
• Gaps: 267/832 - (32%)

  Fly     2 STCSSSEIAEKKRIALAKLQAKKSQLLASAPATNGKSTTS-ATGATQHANNGKSNPNQPQAKSPL 65
            ||.|::    |.:.|.|..:.|||...:|...:|...... ::.||:..||..|
Mosquito   370 STTSNA----KSKAAAAASKKKKSNAYSSDDGSNSDDDRKRSSAATRRKNNTVS----------- 419

  Fly    66 NFYRSPTGEQKKINRSGPTPGDN---------KSSSFLNALKAIKQTSNRELS-----RGAAHPY 116
              |:..:|::       ||..|:         ::::.|.|.:...:|..|.:.     |||....
Mosquito   420 --YKEESGDE-------PTDSDDLLEVDQEAEEAAAALAAEEEKAETIERIIGRRRGRRGATGAV 475

  Fly   117 QRPNGGNERNKPTL----SLSSDKEKPVAVLLGNSITCNLYLISTHRFAAQTSGY---------- 167
            .......|...|.:    .:..::|:                 ...:|..:.:|:
Mosquito   476 TTVYAIEENGDPNVLGGEGVGREQEE-----------------EEEQFLIKWTGWSYLHCTWESE 523

  Fly   168 ---HEQLVTVFKNMPTKCY---DGQTRIW------SFDLSDYQSLKTHAAD-LKPYVHMNGI--- 216
               .||.|...|.:..  |   :.|...|      ..|:..|:..:....| ||.|.|:..|
Mosquito   524 ETLREQKVKGMKKLEN--YIKREQQLEYWRKYQAGPEDIDYYECQQELQQDLLKSYYHVERIIAQ 586

  Fly   217 -------------------------------------PKKVLD---------------------- 222
                                                 .:|:::
Mosquito   587 ANKAEEGDSGLEYLCKWESLPYSDSTWEDAGLIRRKWQQKIVEFHEREESRRTPSKHCKAIRYRP 651

  Fly   223 ----LCGQPPVVPERSVLASIEPKLADQLMPFQQDGVCFAI---AQKGRIMICDEMGLGKTYQAL 280
                |..||..:.|...|     ||.|    :|.||:.:.|   .:...:::.||||||||.|.:
Mosquito   652 NFKHLKQQPEYLGEERGL-----KLRD----YQMDGLNWLILTWCKDNSVILADEMGLGKTIQTI 707

  Fly   281 AVADY-FKDD---WPLLVCTTASTRDSWAKHIMDLLPKVPIHYVQVLNNNQLYVGEAK------- 334
            ....| ||..   .|.|.....||..:|.:......|::         |...|:|:.:
Mosquito   708 CFLYYLFKSQQLYGPFLCVVPLSTMPAWQREFGIWAPEL---------NVVTYLGDVQSREIIRQ 763

  Fly   335 --------------VLITSYNMMERHEDKLMQRKFGF--IIFDESHTLKNSKAKCTTTAKRLTDQ 383
                          .::|:|.::.:  ||......|:  ::.||:|.|||..:......|.....
Mosquito   764 YEWCYESTKKLKFNAILTTYEILLK--DKTFLGSIGWASLLVDEAHRLKNDDSLLYKALKEFDTN 826

  Fly   384 AKRVVLLSGTPALSRPLELFTQLQMI-DGKFMNFMEFTTRYCDGKQSTFGWDANGQSNLEELKVI 447
            .:  :|::|||..:...||:..|..| ..:|.::.:|...|             |.:..::....
Mosquito   827 HR--LLITGTPLQNSLKELWALLHFIMPERFESWDDFERNY-------------GNTTNDKSYTK 876

  Fly   448 LHLK---YMLRRTKVEVLPQLAEKNRETVVLDPALV------WTNAETKETLDAFNKELKTAKGR 503
            ||.:   |:|||.|.:|...|..|..:.:.::...:      |.   ..:..||..|.:|.:.|.
Mosquito   877 LHKELEPYILRRVKKDVEKSLPAKVEQILRVEMTSIQRQYYKWI---LSKNFDALRKGMKGSVGT 938

  Fly   504 ATEEIL--------------LRFYARTAEVKTRAVCAYLKTLVKEQKKFIIF---------AHHR 545
            ....::              :.|     |.:..:....::.|:|...|.::.         ..||
Mosquito   939 FLNIVIELKKCCNHAALTRPIEF-----ETQRNSQQDVVQQLLKGSGKLVLLDKLLCRLKETGHR 998

  Fly   546 V--------MMDAISDFLSGLKVHYIRIDGQTRSDHRSDSVDTFQKKSSCKVA-LLSLKACNSGI 601
            |        |:|.::::|......:.|:||..:.:.|..::|.|..:.|.... |||.:|...||
Mosquito   999 VLIFSQMVRMLDILAEYLQKRHFSFQRLDGSIKGELRKQALDHFNAEGSTDFCFLLSTRAGGLGI 1063

  Fly   602 TLTAAEIIVFAELDWNPSTLAQAESRAHRIGQTKPV-ICRYLIAHNTADDII 652
            .|..|:.::..:.||||....||::|||||||...| |.|.:.||:..::|:
Mosquito  1064 NLATADTVIIFDSDWNPQNDLQAQARAHRIGQKNQVNIYRLVTAHSVEENIV 1115

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	16/78 (21%)
		HepA	<233..666	CDD:440319	114/493 (23%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	53/242 (22%)
Chd1	XP_061511441.1	None