Protein Alignment Marcal1 and brm

DIOPT Version :10

• Sequence 1: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_061518350.1
• Gene: brm / 1272575
• VectorBaseID: AGAMI1_001677
• Length: 1667
• Species: Anopheles gambiae
• Alignment Length: 891
• Identity: 196/891 - (21%)
• Similarity: 325/891 - (36%)
• Gaps: 244/891 - (27%)

  Fly    10 AEKKRIALAKLQAKKSQLLASAPATNGKSTTSATGATQHANN----GKSNPNQPQAKSPLNFYRS 70
            ||:||      :.|..:.|||. ..:||....     .|.||    |:.|      |:.:|::.:
Mosquito   585 AERKR------RQKHQEFLASV-LQHGKDFKE-----YHRNNIAKLGRLN------KAVMNYHAN 631

  Fly    71 PTGEQKKINRSGPTPGDNKSSSFLNALKAIKQTSNRELSRGAAHPYQRPNGGNERNKPTLSLSSD 135
            ...||||                  ..:.|::...|.|.......|::            .:...
Mosquito   632 AEREQKK------------------EQERIEKERMRRLMAEDEEGYRK------------LIDQK 666

  Fly   136 KEKPVAVLLGNS---ITCNLYLISTHRFAAQ------------------TSGYHEQL-------- 171
            |:|.:|.||..:   |:....::..|:...:                  .||..|.|
Mosquito   667 KDKRLAFLLSQTDEYISNLTEMVKQHKVDQKKKQDDEIQRKKQLKRHILESGDIEHLDEHCEASD 731

  Fly   172 --VTVFKNMPTKCYDGQTRIWSFDLSDYQSLKTHAADLKPYVHMNG---------------IPKK 219
              |||.:....|...|....:..||..:  |:.|..  ..||..:|               .|::
Mosquito   732 CRVTVMETATGKMISGDDAPFLRDLHSW--LQLHPG--WEYVISDGDADDDEEESEGGKKKTPEE 792

  Fly   220 VLDLCGQPPVVPER----------------SVLASIEPKLADQ--------LMPFQQDGVCFAIA 260
            .|....:...|.::                |:..::..|:.:|        |..:|..|:.:.::
Mosquito   793 ELSDDAKTKEVIQKAKVEDDEYKTEEQTYYSIAHTVHEKVTEQASILVNGKLKEYQIKGLEWLVS 857

  Fly   261 QKGRIM---ICDEMGLGKTYQALAVADYF----KDDWPLLVCTTASTRDSWAKHIMDLLPKVPI- 317
            .....:   :.||||||||.|.:|:..|.    |::.|.||....||..:|........|.|.:
Mosquito   858 LFNNNLNGILADEMGLGKTIQTIALVTYLMEKKKNNGPYLVIVPLSTLSNWVLEFEKWAPAVGVV 922

  Fly   318 ---------HYVQVLNNNQLYVGEAKVLITSYNMMERHEDKLMQRKFGFIIFDESHTLKNSKAKC 373
                     ..||    ||:...:..||:|:|..:.:.:..|.:..:.::|.||.|.:||...|.
Mosquito   923 AYKGSPAGRRAVQ----NQMKATKFNVLLTTYEYVIKDKAVLAKISWKYMIIDEGHRMKNHHCKL 983

  Fly   374 TTTAKRLTDQAKRVVLLSGTPALSRPLELFTQLQMIDGKFMNFMEFTTRYCDGKQSTFGWDANGQ 438
            |.......:...| :||:|||..::..||:..|..:............::.:...:|.|    .:
Mosquito   984 TQVLNTHYNAPHR-LLLTGTPLQNKLPELWALLNFLLPSIFKSCSTFEQWFNAPFATTG----EK 1043

  Fly   439 SNLEELKVILHLK--------YMLRRTKVEVLPQLAEKNRETVVLDPA----LVWTNAETKETLD 491
            ..|.|.:.||.::        ::|||.|.||..||.:|....|..|.:    :::.:.::|..|.
Mosquito  1044 VELNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPDKVEYIVKCDMSGLQRVLYKHMQSKGVLL 1108

  Fly   492 AFNKELKTAKGRATEEILLRFYARTAEVKTRAVCAYL----------------------KTLVKE 534
            ....| |..||:...:.|:     ...|:.|.:|.:.                      ..|.:.
Mosquito  1109 TDGSE-KGNKGKGGAKALM-----NTIVQLRKLCNHPFMFQHIEEKYCDHIGVQGTVTGPDLYRA 1167

  Fly   535 QKKFIIF---------AHHRVM--------MDAISDFLSGLKVHYIRIDGQTRSDHRSDSVDTFQ 582
            ..||.:.         ..|||:        |..|.|:||.....|:|:||.|:|:.|.|.:..|.
Mosquito  1168 SGKFELLDRILPKLKATGHRVLLFCQMTQCMTIIEDYLSWRGFGYLRLDGTTKSEERGDLLKKFN 1232

  Fly   583 KKSS-CKVALLSLKACNSGITLTAAEIIVFAELDWNPSTLAQAESRAHRIGQTKPVICRYLIAHN 646
            .|:| ..:.|||.:|...|:.|..|:.:|..:.||||....||:.|||||||...|....|:..|
Mosquito  1233 SKNSDYFLFLLSTRAGGLGLNLQTADTVVIFDSDWNPHQDLQAQDRAHRIGQRNEVRVLRLMTVN 1297

  Fly   647 TADDIIWNMLK---NKQEVLSKVGIFAENLQKATHTAAPTSSHKIEEYFSPSTSTSLEPERNSIK 708
            :.::.|....:   |..|.:.:.|:|.   ||:|.:                       ||....
Mosquito  1298 SVEERILAAARYKLNMDEKVIQAGMFD---QKSTGS-----------------------ERQQFL 1336

  Fly   709 QYFSTIPAKEPPEQNNNTEMTKVNKAESDIAAFFNDDDDEAFLELD 754
            |........:..|:|...:...:|...|.     .||:.|.|.::|
Mosquito  1337 QSILHQDEMDEEEENEVPDDEMINLMISR-----TDDELELFKKMD 1377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	16/98 (16%)
		HepA	<233..666	CDD:440319	128/528 (24%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	56/233 (24%)
brm	XP_061518350.1	None