Protein Alignment Marcal1 and Chd4

DIOPT Version :10

• Sequence 1: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Sequence 2: XP_006237458.1
• Gene: Chd4 / 117535
• RGDID: 620064
• Length: 1956
• Species: Rattus norvegicus
• Alignment Length: 746
• Identity: 169/746 - (22%)
• Similarity: 291/746 - (39%)
• Gaps: 159/746 - (21%)

  Fly   116 YQRPN----------GGNE------RNKPTLSLSSDKE------KPVAVLLGNSITCNLYLISTH 158
            |||.|          ||:|      :||.......::.      ||..:::             |
  Rat   574 YQRKNDMDEPPSGDFGGDEEKSRKRKNKDPKFAEMEERFYRYGIKPEWMMI-------------H 625

  Fly   159 RF---AAQTSGYHEQLVTVFKNMPTKCYDGQTRIW---SFDLSDY----QSLKTH-----AADLK 208
            |.   :....|:...|:. ::::|   ||..:  |   ..::.||    ||...|     ..:.:
  Rat   626 RILNHSVDKKGHVHYLIK-WRDLP---YDQAS--WESEDVEIQDYDLFKQSYWNHRELMRGEEGR 684

  Fly   209 PYVHMNGIPKKVLDLCGQPPVVP--ERSVLASIEPKLAD----QLMPFQQDG---VCFAIAQKGR 264
            |...:..:..:.|:   :||..|  :.:|....:|:..|    .|.|:|.:|   :.|:.||...
  Rat   685 PGKKLKKVKLRKLE---RPPETPTVDPTVKYERQPEYLDATGGTLHPYQMEGLNWLRFSWAQGTD 746

  Fly   265 IMICDEMGLGKTYQ-ALAVADYFKD---DWPLLVCTTASTRDSWAKHIMDLLPKV-PIHYV---- 320
            .::.||||||||.| |:.:...:|:   ..|.||....||..:|.:......|.: .:.||
  Rat   747 TILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLVSAPLSTIINWEREFEMWAPDMYVVTYVGDKD 811

  Fly   321 --QVLNNNQLYV------GEAK-------------VLITSYNMMERHEDKLMQRKFGFIIFDESH 364
              .::..|:...      |..|             ||:|||.::......|....:..:|.||:|
  Rat   812 SRAIIRENEFSFEDNAIRGGKKASRMKKEASVKFHVLLTSYELITIDMAILGSIDWACLIVDEAH 876

  Fly   365 TLKNSKAKCTTTAKRLTDQAKRVVLLSGTPALSRPLELFTQLQMI-DGKFMNFMEFTTRYCDGKQ 428
            .|||:::|........:.|.|  :||:|||..:...|||..|..: ..:|.|...|...:.|..:
  Rat   877 RLKNNQSKFFRVLNGYSLQHK--LLLTGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFADIAK 939

  Fly   429 STFGWDANGQSNLEELKVILHLKYMLRRTKVEVLPQLAEKNRETVV---LDPALVWTNAETKETL 490
                     :..:::|..:|. .:||||.|.:|...:..|. |.:|   |.|    ...:..:.:
  Rat   940 ---------EDQIKKLHDMLG-PHMLRRLKADVFKNMPSKT-ELIVRVELSP----MQKKYYKYI 989

  Fly   491 DAFNKELKTAKGRATEEILLR----------------------------FYARTAEVKTRAVCAY 527
            ...|.|...|:|...:..||.                            .|..:|.::.......
  Rat   990 LTRNFEALNARGGGNQVSLLNVVMDLKKCCNHPYLFPVAAMEAPKMPNGMYDGSALIRASGKLLL 1054

  Fly   528 LKTLVKEQK----KFIIFAHHRVMMDAISDFLSGLKVHYIRIDGQTRSDHRSDSVDTFQKKSSCK 588
            |:.::|..|    :.:||:....|:|.:.|||......|.||||....:.|.:::|.|....:.:
  Rat  1055 LQKMLKNLKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQ 1119

  Fly   589 VA-LLSLKACNSGITLTAAEIIVFAELDWNPSTLAQAESRAHRIGQTKPVICRYLIAHNTADDII 652
            .. |||.:|...||.|..|:.::..:.||||....||.||||||||.|.|:....:...:.::.|
  Rat  1120 FCFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERI 1184

  Fly   653 WNMLKNKQ---EVLSKVGIFAENLQKATHTAAPTSSHKIEEYFSPSTS----TSLEPERNSIKQY 710
            ..:.|.|.   .::.:.|:.::....:............||.|....:    .:.|.|.:|:..|
  Rat  1185 TQVAKKKMMLTHLVVRPGLGSKTGSMSKQELDDILKFGTEELFKDEATDGGGDNKEGEDSSVIHY 1249

  Fly   711 FSTIPAKEPPEQNNNTEMTKVNKAESDIAAF 741
            ......:......:.||.|::......:::|
  Rat  1250 DDKAIERLLDRNQDETEDTELQGMNEYLSSF 1280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	12/70 (17%)
		HepA	<233..666	CDD:440319	128/509 (25%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	63/242 (26%)
Chd4	XP_006237458.1	CHDNT	164..217	CDD:462357
		PHD1_CHD_II	372..414	CDD:277006
		PHD2_CHD_II	451..493	CDD:277007
		CD1_tandem_CHD3-4_like	498..576	CDD:349314	1/1 (100%)
		CD2_tandem_CHD3-4_like	619..673	CDD:349309	13/72 (18%)
		PLN03142	724..>1281	CDD:215601	137/574 (24%)
		DEXHc_CHD4	726..957	CDD:350814	63/242 (26%)
		DUF1087	1302..1345	CDD:461922
		CHDII_SANT-like	1409..1549	CDD:461920
		CHDCT2	1770..1915	CDD:462358