DRSC/TRiP Functional Genomics Resources

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Protein Alignment Marcal1 and chd2

DIOPT Version :10

Sequence 1:NP_608883.1 Gene:Marcal1 / 33709 FlyBaseID:FBgn0031655 Length:755 Species:Drosophila melanogaster
Sequence 2:XP_002933353.2 Gene:chd2 / 100497210 XenbaseID:XB-GENE-950755 Length:1809 Species:Xenopus tropicalis


Alignment Length:567 Identity:128/567 - (22%)
Similarity:224/567 - (39%) Gaps:120/567 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   246 QLMPFQQDG---VCFAIAQKGRIMICDEMGLGKTYQALAVADYFKD----DWPLLVCTTASTRDS 303
            :|..:|.:|   :..:..:...:::.||||||||.|.::...|...    ..|.|:....||..|
 Frog   486 ELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHLHLLYGPFLLVVPLSTLTS 550

  Fly   304 WAKHIMDLLPKVPIHYVQVLNNNQLYVGEA---------------------KVLITSYNMMERHE 347
            |.:......|.:         |..:|:|:.                     ..|:|:|.::.:.:
 Frog   551 WQREFEVWAPDI---------NVVVYIGDLGSRNTIREYEWVHQQSKKMKFNALLTTYEILLKDK 606

  Fly   348 DKLMQRKFGFIIFDESHTLKNSKAKCTTTAKRLTDQAKRVVLLSGTPALSRPLELFTQLQMI-DG 411
            ..|....:.|:..||:|.|||..:....|.......|:  :|::|||..:...||::.|..| ..
 Frog   607 AVLSSINWAFLGVDEAHRLKNDDSLLYKTLIEFKSNAR--LLITGTPLQNSLKELWSLLHFIMPE 669

  Fly   412 KFMNFMEFTTRYCDGKQSTFGWDANGQSNLEELKVILHLKYMLRRTKVEVLPQLAEKNRETVVLD 476
            ||..:.:|..::..|:.       ||..:|.  ||:  ..::|||.|.:|...|..|..:.:.::
 Frog   670 KFECWEDFEDQHGKGRD-------NGYQSLH--KVL--EPFLLRRVKKDVEKSLPAKVEQILRVE 723

  Fly   477 PALV------W------------TNAETKETLDAFNKELKTAKGRATEEILLRFYARTAEVKTRA 523
            ..::      |            |...|...|:.. .|||......       |..:..|.:..:
 Frog   724 MCVMQKQYYRWILTRNYKALSKGTRGSTSGFLNIV-MELKKCCNHC-------FLIKPEETEKES 780

  Fly   524 VCAYLKTLVKEQKKFI-----------------IFAHHRVMMDAISDFLSGLKVHYIRIDGQTRS 571
            ....|::|::...|.:                 ||:....|:|.::::|:.....:.|:||..:.
 Frog   781 RLDSLQSLIRSSGKLVLLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLAIKHYPFQRLDGSIKG 845

  Fly   572 DHRSDSVDTFQKKSS---CKVALLSLKACNSGITLTAAEIIVFAELDWNPSTLAQAESRAHRIGQ 633
            :.|..::|.|..:.|   |  .|||.:|...||.|.:|:.:|..:.||||....||::|||||||
 Frog   846 ELRKQALDHFNAEGSEDFC--FLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQ 908

  Fly   634 TKPVICRYLIAHNTADDIIWNMLKNKQEVLSKVGIFAENLQKATHTAAPTSS--------HKIE- 689
            .|.|....|:...|.::.|....|.|. ||..:.|  :.:.....|....:|        :|.| 
 Frog   909 KKQVNIYRLVTRGTVEEDIIERAKKKM-VLDHLVI--QRMDTTGRTVLDNNSGSSNCNPFNKDEL 970

  Fly   690 ---------EYFSPSTSTSLEPERNSIKQYFSTIPAKEPPEQNNNTE 727
                     :.|..:....|||:...|.:.......:|....::.|:
 Frog   971 AAILKFGAADLFKETEGEELEPQEMDIDEILRLAETRENEPSSSATD 1017

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Marcal1NP_608883.1 HARP 160..216 CDD:462166
HepA <233..666 CDD:440319 116/486 (24%)
DEXHc_HARP_SMARCAL1 247..456 CDD:350768 54/237 (23%)
chd2XP_002933353.2 CD1_tandem_CHD1-2_like 264..346 CDD:349313
CD2_tandem_CHD1-2_like 379..450 CDD:349308
DEXHc_CHD2 467..703 CDD:350812 54/238 (23%)
PLN03142 471..>1005 CDD:215601 126/553 (23%)
CDH1_2_SANT_HL1 1132..1220 CDD:465731
DUF4208 1466..1548 CDD:464035
Blue background indicates that the domain is not in the aligned region.

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