DRSC/TRiP Functional Genomics Resources

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Protein Alignment Marcal1 and chd1

DIOPT Version :10

Sequence 1:NP_608883.1 Gene:Marcal1 / 33709 FlyBaseID:FBgn0031655 Length:755 Species:Drosophila melanogaster
Sequence 2:XP_031749152.1 Gene:chd1 / 100485675 XenbaseID:XB-GENE-960477 Length:1797 Species:Xenopus tropicalis


Alignment Length:619 Identity:156/619 - (25%)
Similarity:254/619 - (41%) Gaps:131/619 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   201 KTHAADLKPYVHMN---GIPKKVLDLCGQPPVVPERSVLASIEPKLAD-----QLMPFQQDGV-- 255
            |...|.:..|:..|   .||.|...:..|.|    |.|....:|....     :|..:|.||:  
 Frog   431 KKFQARIDEYISRNQSKTIPFKECKVLKQRP----RFVALKKQPSYIGGNKQLELRDYQLDGLNW 491

  Fly   256 -----CFAIAQKGR-IMICDEMGLGKTYQALAVADYFKDD----WPLLVCTTASTRDSWAKHIMD 310
                 |     ||. .::.||||||||.|.::..:|...:    .|.|:....||..||.:.|..
 Frog   492 LAHSWC-----KGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQI 551

  Fly   311 LLPKVPIHYVQVLNNNQLYVGE---------------------AKVLITSYNMMERHEDKLMQRK 354
            ..|         |.|..:|:|:                     ..||:|:|.::.:.:..|....
 Frog   552 WAP---------LMNAVVYLGDINSRNMIRTHEWMHPQTKRLKLNVLLTTYEILLKDKSFLGGVN 607

  Fly   355 FGFIIFDESHTLKNSKAKCTTTAKRLTD-QAKRVVLLSGTPALSRPLELFTQLQMI-DGKFMNFM 417
            :.||..||:|.|||..   :...|.|.| ::...:|::|||..:...||::.|..| ..||.::.
 Frog   608 WAFIGVDEAHRLKNDD---SLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWE 669

  Fly   418 EFTTRYCDGKQSTFGWDANGQSNLEELKVILHLKYMLRRTKVEVLPQLAEKNRETVVLDPA---- 478
            :|...:  ||...:|: |:....||        .::|||.|.:|...|..|..:.:.::.:    
 Frog   670 DFEEEH--GKGREYGY-ASLHKELE--------PFLLRRVKKDVEKSLPAKVEQILRVEMSASQK 723

  Fly   479 --LVWTNAETKETLDAFNK-----------ELKTAKG-----RATEEILLRFYARTAEV------ 519
              ..|......:.|...:|           |||....     :..||  ..||.|...:      
 Frog   724 QYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPEE--NEFYNRQEALQHLIRS 786

  Fly   520 --KTRAVCAYLKTLVKEQKKFIIFAHHRVMMDAISDFLSGLKVHYIRIDGQTRSDHRSDSVDTFQ 582
              |...:...|..|.:...:.:||:....|:|.::::|...:..:.|:||..:.:.|..::|.|.
 Frog   787 SGKLILLDKLLVRLRERGNRVLIFSQMVRMLDILAEYLKSRQFPFQRLDGSIKGEVRKQALDHFN 851

  Fly   583 KKSS---CKVALLSLKACNSGITLTAAEIIVFAELDWNPSTLAQAESRAHRIGQTKPVICRYLIA 644
            .:.|   |  .|||.:|...||.|.:|:.:|..:.||||....||::|||||||.|.|....|:.
 Frog   852 AEGSEDFC--FLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVT 914

  Fly   645 HNTADDIIWNMLKNKQEVLSKVGIFAENLQKATHTAAPTSSHKIEEYFSPSTSTSLEPER-NSIK 708
            ..:.::.|....|.|. ||..:.|  :.:.....|...|.|       :||:||....|. .:|.
 Frog   915 KGSVEEDIIERAKKKM-VLDHLVI--QRMDTTGKTVLHTGS-------TPSSSTPFNKEELAAIL 969

  Fly   709 QYFSTIPAKEP------PEQNNNTEMTKVNKAES 736
            ::.:....|||      |::.:..|:.|  :||:
 Frog   970 KFGAEELFKEPEGEEEEPQEMDIDEILK--RAET 1001

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Marcal1NP_608883.1 HARP 160..216 CDD:462166 4/17 (24%)
HepA <233..666 CDD:440319 129/505 (26%)
DEXHc_HARP_SMARCAL1 247..456 CDD:350768 63/243 (26%)
chd1XP_031749152.1 CD1_tandem_CHD1-2_like 270..354 CDD:349313
CD2_tandem_CHD1-2_like 387..443 CDD:349308 3/11 (27%)
PLN03142 464..>1000 CDD:215601 144/579 (25%)
CDH1_2_SANT_HL1 1123..1208 CDD:477096
DUF4208 1491..1581 CDD:464035
U2AF_lg 1669..>1778 CDD:273727
HisXaaSer_A3 <1705..1744 CDD:439608
Blue background indicates that the domain is not in the aligned region.

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