Protein Alignment Jon25Bi and GZMM

DIOPT Version :10

• Sequence 1: NP_001033873.1
• Gene: Jon25Bi / 33708
• FlyBaseID: FBgn0020906
• Length: 266
• Species: Drosophila melanogaster
• Sequence 2: NP_005308.2
• Gene: GZMM / 3004
• HGNCID: 4712
• Length: 257
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 77/280 - (27%)
• Similarity: 113/280 - (40%)
• Gaps: 56/280 - (20%)

  Fly     6 VLALALAAVSAETVQQVHPKDLPKDTKINGRIVNGYPAYEGKAPYTVGLGFSGNGGWWCGGSIIA 70
            :|.|||.|:|.             .:....:|:.|........||...|  ..||...|||.::.
Human     8 LLVLALGALSV-------------GSSFGTQIIGGREVIPHSRPYMASL--QRNGSHLCGGVLVH 57

  Fly    71 HDWVLTAAHC-TNGASQVTIYYGATWRTNAQFTHTVGSGDF-------IQNHNWPNQNG--NDIA 125
            ..|||||||| ....:|:.:..|         .||:.|...       ||:..:.....  ||:|
Human    58 PKWVLTAAHCLAQRMAQLRLVLG---------LHTLDSPGLTFHIKAAIQHPRYKPVPALENDLA 113

  Fly   126 LIRTP-HVDFWHMVNKVELPS------FNDRYNMYDNYWAVACGWGLTTAGSQ-PDWMECVDLQI 182
            |::.. .|.....:..:.|||      ...|.:|        .|||||..|.: ...:..:|||:
Human   114 LLQLDGKVKPSRTIRPLALPSKRQVVAAGTRCSM--------AGWGLTHQGGRLSRVLRELDLQV 170

  Fly   183 ISNSECSRT---YGTQPDGILCVST-SGGKSTCSGDSGGPLVLHDGGRLVGVTSWVSGNGCT-AG 242
            :....|:.:   .|:....::|::. |..::.|.||||||||...|..|..|.|: |...|| ..
Human   171 LDTRMCNNSRFWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLARVLSF-SSRVCTDIF 234

  Fly   243 LPSGFTRVTNQLDWIRDNSG 262
            .|...|.|...:.|||..:|
Human   235 KPPVATAVAPYVSWIRKVTG 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon25Bi	NP_001033873.1	Tryp_SPc	36..257	CDD:214473	67/243 (28%)
GZMM	NP_005308.2	Tryp_SPc	26..252	CDD:238113	70/245 (29%)