DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Jon25Bii and zgc:154142

DIOPT Version :9

Sequence 1:	NP_001285608.1	Gene:	Jon25Bii / 33707	FlyBaseID:	FBgn0031654	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_001092710.1	Gene:	zgc:154142 / 555481	ZFINID:	ZDB-GENE-070615-2	Length:	1090	Species:	Danio rerio

Alignment Length:	280	Identity:	84/280 - (30%)
Similarity:	118/280 - (42%)	Gaps:	72/280 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 SIEGRITNGYPAYEGKVPYIVGLGFSSDSG----GWWCGGSIIGHTWVITAAHC-------TH-- 89
            ::..||.||.||.....|:.|.:....||.    |..|||::|...||:|||||       .|
Zfish   582 AVNTRIVNGEPANPHSWPWQVSMQVLRDSEPPMLGHTCGGTLIHKNWVLTAAHCFIRYADELHRW 646

  Fly    90 ----GAHSVTIYYGA--LWRLQAQYTH------TVGSGHFRQHSDYNTNNLNNDISLIN------ 136
                |.|::|:....  .:.:...|.|      ||.:..|             ||:|:.
Zfish   647 KMCLGKHNLTVSESTEQCFNVLGIYRHEGFQYPTVPTVEF-------------DIALVRLDGEVT 698

  Fly   137 -TPHVDFWHLINKVELPDGNERHDSFAGWWALASGWGRPCDSCG------VSDYLNCVDSQIITR 194
             |.|:||..|.:..||..|.::        ..|:|||   |..|      |::.||.|...::..
Zfish   699 ATEHIDFACLPSFEELLPGGKK--------CYATGWG---DETGNSTAPKVAETLNQVALPVVPY 752

  Fly   195 DECSSV-YGTDVITDNVIC---TSTPGGKSTCAGDSGGPLVLHDRS----KLVGVTSFVAASGCT 251
            :.|..: |....:..::||   ||....||.|.||||||||..|..    ::.|:||| ...||.
Zfish   753 ETCKRMDYWWFQVKTSMICCGYTSPDELKSVCQGDSGGPLVCQDSPSAPWEVHGITSF-GPIGCV 816

  Fly   252 -SGLPDGFTRVTSYLDWIRD 270
             ...|..|||.:.||.||.:
Zfish   817 FDKKPSVFTRSSVYLPWIEN 836

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon25Bii	NP_001285608.1	Tryp_SPc	42..268	CDD:214473	82/272 (30%)
Jon25Bii	NP_001285608.1	Tryp_SPc	43..271	CDD:238113	83/275 (30%)
zgc:154142	NP_001092710.1	CUB	57..159	CDD:238001
		CUB	172..280	CDD:238001
		CUB	310..420	CDD:238001
		CUB	432..546	CDD:238001
		Tryp_SPc	586..834	CDD:214473	82/272 (30%)
		Tryp_SPc	587..837	CDD:238113	83/275 (30%)
		CUB	850..959	CDD:238001
		CUB	971..1080	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24991
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000