DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon25Bii and prss27

DIOPT Version :9

Sequence 1:	NP_001285608.1	Gene:	Jon25Bii / 33707	FlyBaseID:	FBgn0031654	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	288	Identity:	95/288 - (32%)
Similarity:	128/288 - (44%)	Gaps:	51/288 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 VPLKDA-------VLGSGSGS-------IEGRITNGYPAYEGKVPYIVGLGFSSDSGGWWCGGSI 75
            |||..|       :||...|:       :..||..|..|.||:.|:.|..   .::||.:|||::
Frog     2 VPLLQALLLLTPGLLGITPGATDCGIPLVSSRIMGGQSAQEGQWPWQVSF---RNNGGHFCGGTL 63

  Fly    76 IGHTWVITAAHC---THGAHSVTIYYGALWRLQA---QYTHTVGSGHFRQHSDYNTNNLNNDISL 134
            |...:||:||||   :..|.|||...||....|.   |....|.|.  ..:..|.....:.||||
Frog    64 ISKQYVISAAHCFPSSSSASSVTAVLGAYMIDQPDGNQVAIPVQSA--TNYPSYVNEGDSGDISL 126

  Fly   135 IN--TPHVDFWHLINKVELPDGNERHDSFAGWWALASGWGR-PCDSCGVSDY-LNCVDSQIITRD 195
            :.  :| |.|.:.|..|.||.......:....|  .:|||. ..|...||.. |..|...:|..:
Frog   127 VQLASP-VTFTNYILPVCLPADTVTFPTGLQCW--VTGWGNIASDVSLVSPMTLQEVAVPLIDAN 188

  Fly   196 ECSSV------YGTDVIT--DNVICTS-TPGGKSTCAGDSGGPLVLHDRSK--LVGVTSFVAASG 249
            ||:::      |||..|:  .::||.. ..|||.:|.||||||||.....:  |.||.||  ..|
Frog   189 ECNALYQTPNSYGTSSISVHSDMICAGFINGGKDSCQGDSGGPLVCSSSGQWFLAGVVSF--GEG 251

  Fly   250 CTSGL-PDGFTRVTSYLDWIRDHTGISY 276
            |.... |..:|.:.||.|||     :||
Frog   252 CGQAYRPGVYTLMPSYTDWI-----VSY 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon25Bii	NP_001285608.1	Tryp_SPc	42..268	CDD:214473	84/247 (34%)
Jon25Bii	NP_001285608.1	Tryp_SPc	43..271	CDD:238113	85/249 (34%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113	83/246 (34%)
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910