Protein Alignment Jon25Bii and Ctsg

DIOPT Version :10

• Sequence 1: NP_608882.1
• Gene: Jon25Bii / 33707
• FlyBaseID: FBgn0031654
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_031826.1
• Gene: Ctsg / 13035
• MGIID: 88563
• Length: 261
• Species: Mus musculus
• Alignment Length: 256
• Identity: 75/256 - (29%)
• Similarity: 111/256 - (43%)
• Gaps: 54/256 - (21%)

  Fly    37 GSIEGRITNGYPAYEGKVPYIVGLGFSSDSGGWWCGGSIIGHTWVITAAHC-------THGAHSV 94
            |...|:|..|..|.....||:..|...|..|...|||.::...:|:|||||       |.|||::
Mouse    15 GDEAGKIIGGREARPHSYPYMAFLLIQSPEGLSACGGFLVREDFVLTAAHCLGSSINVTLGAHNI 79

  Fly    95 TIYYGALWRLQAQYTHTVGSGHFR--QHSDYNTNNLNNDISLINTPHVDFWHL---------INK 148
            .:      |.:.|...||    .|  :|.|||..|:.|||.|:        .|         :..
Mouse    80 QM------RERTQQLITV----LRAIRHPDYNPQNIRNDIMLL--------QLRRRARRSGSVKP 126

  Fly   149 VELPDGNERHDSFAGWWALASGWGRPCDSCGVSDYLNCVDSQIITRDECSS---VYGTDVITDNV 210
            |.||..:::..  .|.....:||||...|.| ::.|..|..::.....|::   .|.    :...
Mouse   127 VALPQASKKLQ--PGDLCTVAGWGRVSQSRG-TNVLQEVQLRVQMDQMCANRFQFYN----SQTQ 184

  Fly   211 ICTSTP-GGKSTCAGDSGGPLVLHDRSKLVGVTSFVAASGCTSGLPDG-FTRVTSYLDWIR 269
            ||...| ..||...||||||||..:.::  |:.|:    |..:|.|.. ||::.|::.||:
Mouse   185 ICVGNPRERKSAFRGDSGGPLVCSNVAQ--GIVSY----GSNNGNPPAVFTKIQSFMPWIK 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jon25Bii	NP_608882.1	Tryp_SPc	42..268	CDD:214473	71/248 (29%)
Ctsg	NP_031826.1	Tryp_SPc	21..241	CDD:238113	73/250 (29%)
		Important for antimicrobial activity. /evidence=ECO:0000250|UniProtKB:P08311	21..25		1/3 (33%)
		Important for antimicrobial activity. /evidence=ECO:0000250|UniProtKB:P08311	97..111		8/13 (62%)