DRSC/TRiP Functional Genomics Resources

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Protein Alignment Jon25Biii and C1S

DIOPT Version :9

Sequence 1:NP_608881.1 Gene:Jon25Biii / 33706 FlyBaseID:FBgn0031653 Length:258 Species:Drosophila melanogaster
Sequence 2:NP_001725.1 Gene:C1S / 716 HGNCID:1247 Length:688 Species:Homo sapiens


Alignment Length:280 Identity:70/280 - (25%)
Similarity:103/280 - (36%) Gaps:50/280 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 ASASAFDEKVFVKDLPKATKIEG----------RITNGYAAPEGKAPYTVGLGFSGGWWCGGSII 67
            |...::..:|...:|||...:.|          ||..|..|.....|:.|   |....|.||::|
Human   404 AGNGSWVNEVLGPELPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQV---FFDNPWAGGALI 465

  Fly    68 AHDWVLTAEHCIGDAASVIVYFGATWRTNAQ------------FTH--------TVGNGNFIKHS 112
            ...|||||.|.:.......:|.|:|....::            |.|        ..|..||    
Human   466 NEYWVLTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNF---- 526

  Fly   113 NADIALIRIPH-VDFWHMVNKVELPSYNDRYNNYNEWWAVACGWGGTYDGS----------PLPD 166
            :.||||:|:.. |.....|:.:.||..:..||..:....:..|||.|....          |:..
Human   527 DNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAP 591

  Fly   167 WLQCVDLQIVHNEECGWTYGSVGDNVICTRTVDGKSICGGDSGGPLVTHD-GSKLVGVSNFVSSN 230
            ..:|.::::.........| ....|:||.....|...|.|||||.....| ..|....:..:.|.
Human   592 LRKCKEVKVEKPTADAEAY-VFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSW 655

  Fly   231 GCQSGAPAGFQRVTYHLDWI 250
            |.|.|....:.||..::|||
Human   656 GPQCGTYGLYTRVKNYVDWI 675

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Jon25BiiiNP_608881.1 Tryp_SPc 36..250 CDD:214473 62/245 (25%)
Tryp_SPc 37..253 CDD:238113 63/246 (26%)
C1SNP_001725.1 CUB 18..129 CDD:238001
FXa_inhibition 143..171 CDD:405372
CUB 175..287 CDD:395345
CCP 294..355 CDD:153056
Sushi 359..421 CDD:395037 4/16 (25%)
Tryp_SPc 438..678 CDD:238113 63/246 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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