DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon25Biii and C1s1

DIOPT Version :9

Sequence 1:	NP_608881.1	Gene:	Jon25Biii / 33706	FlyBaseID:	FBgn0031653	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	NP_001091086.1	Gene:	C1s1 / 50908	MGIID:	1355312	Length:	694	Species:	Mus musculus

Alignment Length:	258	Identity:	66/258 - (25%)
Similarity:	102/258 - (39%)	Gaps:	54/258 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 KIEGRITNGYAAPEGKAPYTVGLGFSGGWWCGGSIIAHDWVLTAEHCIGDAASVIVYFG-----A 91
            ::..||..|..|.....|:.|   |.......|::|...|||||.|.:...:..::|.|     .
Mouse   439 QVHQRIFGGQPAKIENFPWQV---FFNHPRASGALINEYWVLTAAHVLEKISDPLMYVGTMSVRT 500

  Fly    92 TWRTNAQ-------FTH----TVGNGNFIKHSNADIALIRIPH-VDFWHMVNKVELPSYNDRYNN 144
            |...|||       |.|    ...:.|...:.:.||||:::.. |.....|:.:.||..:..||.
Mouse   501 TLLENAQRLYSKRVFIHPSWKKEDDPNTRTNFDNDIALVQLKDPVKMGPKVSPICLPGTSSEYNV 565

  Fly   145 YNEWWAVACGWGGT--------YDGS--PLPDWLQCVDLQ----IVHNEECGWTYGSVGDNVICT 195
            ......:..|||.|        ..|:  |:.....|..::    .|..|:..:|     ||:||.
Mouse   566 SPGDMGLISGWGSTEKKVFVINLRGAKVPVTSLETCKQVKEENPTVRPEDYVFT-----DNMICA 625

  Fly   196 --RTVDGKSICGGDSGG------PLVTHDGSKLVGVSNFVSSNGCQSGAPAGFQRVTYHLDWI 250
              :.||.   |.|||||      |.||.....:.|:.::    |.:.|....:.:|..::|||
Mouse   626 GEKGVDS---CHGDSGGAFAFQVPNVTVPKFYVAGLVSW----GKRCGTYGVYTKVKNYVDWI 681

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon25Biii	NP_608881.1	Tryp_SPc	36..250	CDD:214473	64/252 (25%)
Jon25Biii	NP_608881.1	Tryp_SPc	37..253	CDD:238113	65/253 (26%)
C1s1	NP_001091086.1	CUB	24..135	CDD:238001
		FXa_inhibition	149..177	CDD:373209
		CUB	181..293	CDD:366096
		CCP	307..361	CDD:153056
		CCP	365..428	CDD:153056
		Tryp_SPc	443..681	CDD:214473	64/252 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000