DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Jon25Biii and CG30091

DIOPT Version :9

Sequence 1:	NP_608881.1	Gene:	Jon25Biii / 33706	FlyBaseID:	FBgn0031653	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster

Alignment Length:	292	Identity:	76/292 - (26%)
Similarity:	116/292 - (39%)	Gaps:	70/292 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VFLAILALAVASASAFDEK--VFVKDLPKATKIEGRITNGYAAPEGKAPYTVGLGFSGGWWCGGS 65
            :|..:|.....||...||.  |.::.:||       |..|..|.|.|.|:...:..:..:.||||
  Fly     8 LFAWMLTAGRGSARLLDEDCGVPMQLIPK-------IVGGVDAGELKNPWMALIKTNDEFICGGS 65

  Fly    66 IIAHDWVLTAEHCI-GDAASVIVYFGATWRTNAQFTHTVG------------------------N 105
            :|.:.:||||.||: .|...::.|        .|.|.|:|                        :
  Fly    66 VITNKFVLTAAHCMCTDEECIVKY--------TQLTVTLGVYHLLATGEHNHPHEIYNVERVYIH 122

  Fly   106 GNF-IKHSNADIALIRI-------PHVDFWHMVNKVELPSYNDRYNNYNEWWAVACGWGGTYDGS 162
            .:| |::...||||:|:       |.:....::...:|....|....:     .|.|||.|.:|.
  Fly   123 DSFAIQNYRNDIALLRLQKSIVYKPQIKPLCILLNDQLKPQTDLIQEF-----TAIGWGVTGNGK 182

  Fly   163 PLPDWLQCVDLQIVHNEECGWTYGSVGD-NVICTRTVDGKSICGGDSGGPLVTH---DGSKLVGV 223
             :.:.||.|.:..:..:.|...:....| .:.|..|..|:..|..||||||..|   ||.|....
  Fly   183 -MSNNLQMVKIYRIDRKMCEAAFWYTFDYPMFCAGTAVGRDTCKRDSGGPLYIHMLFDGIKRATQ 246

  Fly   224 SNFVS--SNGCQSGAPAGFQRVT---YHLDWI 250
            ...||  :..|:     ||...|   .|:|:|
  Fly   247 LGIVSTGTEDCR-----GFGMYTDVMGHIDFI 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon25Biii	NP_608881.1	Tryp_SPc	36..250	CDD:214473	66/255 (26%)
Jon25Biii	NP_608881.1	Tryp_SPc	37..253	CDD:238113	67/256 (26%)
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	67/262 (26%)
		Tryp_SPc	37..276	CDD:238113	67/256 (26%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435813
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030