DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon25Biii and F9

DIOPT Version :9

Sequence 1:	NP_608881.1	Gene:	Jon25Biii / 33706	FlyBaseID:	FBgn0031653	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	NP_000124.1	Gene:	F9 / 2158	HGNCID:	3551	Length:	461	Species:	Homo sapiens

Alignment Length:	246	Identity:	65/246 - (26%)
Similarity:	109/246 - (44%)	Gaps:	34/246 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 RITNGYAAPEGKAPYTVGLGFSGGWWCGGSIIAHDWVLTAEHCIGDAASVIVYFGATWRTNAQFT 100
            |:..|..|..|:.|:.|.|......:|||||:...|::||.||:.....:.|..|   ..|.:.|
Human   226 RVVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAG---EHNIEET 287

  Fly   101 -HTVGNGNFIK----HS--------NADIALIRIPHVDFWHMVNKVELP------SYNDRYNNYN 146
             ||....|.|:    |:        |.||||:.:   |...::|....|      .|.:.:..:.
Human   288 EHTEQKRNVIRIIPHHNYNAAINKYNHDIALLEL---DEPLVLNSYVTPICIADKEYTNIFLKFG 349

  Fly   147 EWWAVACGWGGTYDGSPLPDWLQCVDLQIVHNEEC-GWTYGSVGDNVICTRTVD-GKSICGGDSG 209
            ..:  ..|||..:........||.:.:.:|....| ..|..::.:|:.|....: |:..|.||||
Human   350 SGY--VSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRDSCQGDSG 412

  Fly   210 GPLVTH-DG-SKLVGVSNFVSSNGCQSGAPAG-FQRVTYHLDWIRDHTGIS 257
            ||.||. :| |.|.|:.::  ...|......| :.:|:.:::||::.|.::
Human   413 GPHVTEVEGTSFLTGIISW--GEECAMKGKYGIYTKVSRYVNWIKEKTKLT 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon25Biii	NP_608881.1	Tryp_SPc	36..250	CDD:214473	62/237 (26%)
Jon25Biii	NP_608881.1	Tryp_SPc	37..253	CDD:238113	63/239 (26%)
F9	NP_000124.1	GLA	28..92	CDD:214503
		EGF_CA	93..129	CDD:238011
		FXa_inhibition	134..170	CDD:317114
		Tryp_SPc	227..457	CDD:238113	63/239 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910