DRSC/TRiP Functional Genomics Resources

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Protein Alignment jet and KDM2B

DIOPT Version :9

Sequence 1:NP_608880.2 Gene:jet / 33705 FlyBaseID:FBgn0031652 Length:319 Species:Drosophila melanogaster
Sequence 2:XP_011537169.1 Gene:KDM2B / 84678 HGNCID:13610 Length:1353 Species:Homo sapiens


Alignment Length:238 Identity:57/238 - (23%)
Similarity:83/238 - (34%) Gaps:94/238 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly   120 RWLTDELLLPLLANNKKRLWA-VNLNECVNITALSL------QPIIVECK--------------- 162
            ||..|           ||||. ::||.|.:||.|.|      ||:.::..               
Human  1097 RWCCD-----------KRLWTRIDLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINR 1150

  Fly   163 --ELRVLKLSKCQWLTTGAVDAL---------TL-----------------------------HQ 187
              .||.|.||.|.|:   ||.||         ||                             ::
Human  1151 LPGLRDLVLSGCSWI---AVSALCSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNR 1212

  Fly   188 SKLVEF-DISYCGA-IGERCLIIFFRKLNKLTVLSLANTPSVTDQ---VLIQIGNYCRE-LEHIN 246
            |||... ::...|. |.:..|.:..|.:..|:.|.|:....||||   :|..:|...|: |..||
Human  1213 SKLRNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEIN 1277

  Fly   247 VIGCAAISDYGVHALTVHCLRLRTLLIRRCPRVTELSLAPLRQ 289
            :..|..::|        .||.    ..:||..:..:.|...:|
Human  1278 LSDCNKVTD--------QCLS----FFKRCGNICHIDLRYCKQ 1308

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
jetNP_608880.2 leucine-rich repeat 85..110 CDD:275381
AMN1 96..>261 CDD:187754 51/208 (25%)
leucine-rich repeat 111..137 CDD:275381 3/16 (19%)
leucine-rich repeat 138..163 CDD:275381 11/48 (23%)
leucine-rich repeat 164..189 CDD:275381 13/62 (21%)
leucine-rich repeat 190..215 CDD:275381 5/26 (19%)
leucine-rich repeat 216..241 CDD:275381 9/27 (33%)
leucine-rich repeat 242..267 CDD:275381 6/24 (25%)
leucine-rich repeat 268..290 CDD:275381 4/22 (18%)
KDM2BXP_011537169.1 JmjC 182..257 CDD:214721
cupin_like 229..335 CDD:304367
zf-CXXC <615..651 CDD:251032
PHD_KDM2B 661..722 CDD:277114
F-box-like 1071..1111 CDD:289689 7/24 (29%)
leucine-rich repeat 1105..1129 CDD:275381 8/23 (35%)
AMN1 1121..1310 CDD:187754 44/203 (22%)
leucine-rich repeat 1130..1153 CDD:275381 0/22 (0%)
leucine-rich repeat 1154..1177 CDD:275381 11/25 (44%)
leucine-rich repeat 1178..1217 CDD:275381 5/38 (13%)
leucine-rich repeat 1218..1242 CDD:275381 4/23 (17%)
leucine-rich repeat 1243..1272 CDD:275381 10/28 (36%)
leucine-rich repeat 1273..1297 CDD:275381 9/35 (26%)
leucine-rich repeat 1298..1323 CDD:275381 2/11 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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