Protein Alignment jet and FBXL15

DIOPT Version :10

• Sequence 1: NP_608880.2
• Gene: jet / 33705
• FlyBaseID: FBgn0031652
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: XP_054222687.1
• Gene: FBXL15 / 79176
• HGNCID: 28155
• Length: 387
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 84/269 - (31%)
• Similarity: 131/269 - (48%)
• Gaps: 23/269 - (8%)

  Fly    43 DVCWDDVLIPQVAVYLSLKDLFNLRCCSRTAQRFVEAALEKRQELHLSGNNTKNID--------- 98
            |:.|:|||:|.|...:.|:.|..|:..||..:..|        :|||:|  .:..|
Human   108 DLPWEDVLLPHVLNRVPLRQLLRLQRVSRAFRSLV--------QLHLAG--LRRFDAAQVGPQIP 162

  Fly    99 -VAFRVLARCCQRLEVLHLA-CCRWLTDELLLPLLANNKKRLWAVNLNECVNITALSLQPIIVEC 161
             .|...|.|..:.|:.|.|| |..||:||.|:|:||.| .:|.:|.|..|..::..:|..:...|
Human   163 RAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARN-PQLRSVALGGCGQLSRRALGALAEGC 226

  Fly   162 KELRVLKLSKCQWLTTGAVDALTLHQSKLVEFDISYCGAIGERCLIIFFRKLNK-LTVLSLANTP 225
            ..|:.|.|:.|.|:...|:..|......|.|.|::.|..:.:..::...::... |..||||...
Human   227 PRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNA 291

  Fly   226 SVTDQVLIQIGNYCRELEHINVIGCAAISDYGVHALTVHCLRLRTLLIRRCPRVTELSLAPLRQR 290
            :|.|..:.::...|.||.|:::.||..:...||..|..:|..||:|.:|.|..|.|.||:.||:|
Human   292 NVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRLRKR 356

  Fly   291 RLYIDRPQP 299
            .:.||...|
Human   357 GVDIDVEPP 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jet	NP_608880.2	F-box_FBXL15	41..84	CDD:438898	13/40 (33%)
		leucine-rich repeat	85..110	CDD:275381	8/34 (24%)
		AMN1	96..>261	CDD:187754	50/176 (28%)
		leucine-rich repeat	111..137	CDD:275381	14/26 (54%)
		leucine-rich repeat	138..163	CDD:275381	6/24 (25%)
		leucine-rich repeat	164..189	CDD:275381	7/24 (29%)
		leucine-rich repeat	190..215	CDD:275381	4/24 (17%)
		leucine-rich repeat	216..241	CDD:275381	8/24 (33%)
		leucine-rich repeat	242..267	CDD:275381	8/24 (33%)
		leucine-rich repeat	268..290	CDD:275381	11/21 (52%)
FBXL15	XP_054222687.1	F-box_FBXL15	106..147	CDD:438898	15/46 (33%)
		leucine-rich repeat	149..175	CDD:275381	4/25 (16%)
		FBXL3_LRR-like	<158..233	CDD:480268	24/75 (32%)
		leucine-rich repeat	176..202	CDD:275381	14/26 (54%)
		leucine-rich repeat	203..228	CDD:275381	6/24 (25%)
		AMN1	<226..>353	CDD:187754	38/126 (30%)
		leucine-rich repeat	229..254	CDD:275381	7/24 (29%)
		leucine-rich repeat	255..281	CDD:275381	4/25 (16%)
		leucine-rich repeat	282..307	CDD:275381	8/24 (33%)
		leucine-rich repeat	308..332	CDD:275381	7/23 (30%)