DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jet and Fbxl22

DIOPT Version :9

Sequence 1:	NP_608880.2	Gene:	jet / 33705	FlyBaseID:	FBgn0031652	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_780415.1	Gene:	Fbxl22 / 74165	MGIID:	1921415	Length:	236	Species:	Mus musculus

Alignment Length:	75	Identity:	24/75 - (32%)
Similarity:	40/75 - (53%)	Gaps:	5/75 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   226 SVTDQVLIQIGNYCRELEHINVIGCAAISDYGVHALTVHCLRLRTLLIRRCPRVTELSLAPLRQ- 289
            |:.:..|:|:.|.|..|..:.:.||..::|..:..|.:.|.|||||.:..|.|||..:||.:..
Mouse   100 SLVNDFLLQVCNRCPNLTSVTLSGCGHVTDDCLARLLLSCPRLRTLRLENCARVTNRTLAAVAAH 164

  Fly   290 ----RRLYID 295
                :.|::|
Mouse   165 GRALQTLHVD 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jet	NP_608880.2	leucine-rich repeat	85..110	CDD:275381
		AMN1	96..>261	CDD:187754	9/34 (26%)
		leucine-rich repeat	111..137	CDD:275381
		leucine-rich repeat	138..163	CDD:275381
		leucine-rich repeat	164..189	CDD:275381
		leucine-rich repeat	190..215	CDD:275381
		leucine-rich repeat	216..241	CDD:275381	5/14 (36%)
		leucine-rich repeat	242..267	CDD:275381	6/24 (25%)
		leucine-rich repeat	268..290	CDD:275381	10/26 (38%)
Fbxl22	NP_780415.1	F-box-like	3..43	CDD:403981
		LRR 1	15..40
		LRR 2	43..72
		AMN1	45..>200	CDD:187754	24/75 (32%)
		LRR 3	98..123		6/22 (27%)
		leucine-rich repeat	116..141	CDD:275381	6/24 (25%)
		LRR 4	124..149		9/24 (38%)
		leucine-rich repeat	142..167	CDD:275381	10/24 (42%)
		LRR 5	150..175		8/25 (32%)
		leucine-rich repeat	168..193	CDD:275381	2/7 (29%)
		LRR 6	176..201
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900