DRSC/TRiP Functional Genomics Resources

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Protein Alignment jet and Fbxl2

DIOPT Version :9

Sequence 1:NP_608880.2 Gene:jet / 33705 FlyBaseID:FBgn0031652 Length:319 Species:Drosophila melanogaster
Sequence 2:NP_848739.1 Gene:Fbxl2 / 72179 MGIID:1919429 Length:423 Species:Mus musculus


Alignment Length:252 Identity:67/252 - (26%)
Similarity:105/252 - (41%) Gaps:38/252 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    62 DLFNLRCCSRTAQRFVEAALEKRQELHLSGNNTKNIDVAFRVLARCCQRLEVLHLACCRWLTDEL 126
            :..||..|.:..:..:||                        |.|.|:.|:.|.|..|..|.|| 
Mouse   159 EYLNLSWCDQITKEGIEA------------------------LVRGCRGLKALLLRGCTQLEDE- 198

  Fly   127 LLPLLANNKKRLWAVNLNECVNITALSLQPIIVECKELRVLKLSKCQWLTTGAVDALTLHQSKLV 191
            .|..:.|:...|.::||..|..||...:..|...|..|:.|.||.|..||..::.||.|:..:|.
Mouse   199 ALKHIQNHCHELVSLNLQSCSRITDDGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQ 263

  Fly   192 EFDISYCGAIGERCLIIFFRKLNKLTVLSLANTPSVTDQVLIQIGNYCRELEHINVIGCAAISDY 256
            ..:.:.|..:.:....:..|..::|..:.|.....:||..|:|:..:|.:|:.:::..|..|:|.
Mouse   264 VLEAARCSHLTDAGFTLLARNCHELEKMDLEECVLITDSTLVQLSIHCPKLQALSLSHCELITDE 328

  Fly   257 GV-HALTVHC--LRLRTLLIRRCPRVTELSLAPLRQRRLYIDRPQPDVGLNAYNLND 310
            |: |..:..|  .|||.|.:..|..||:.||..|...|          ||....|.|
Mouse   329 GILHLSSSTCGHERLRVLELDNCLLVTDASLEHLENCR----------GLERLELYD 375

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
jetNP_608880.2 leucine-rich repeat 85..110 CDD:275381 3/24 (13%)
AMN1 96..>261 CDD:187754 46/165 (28%)
leucine-rich repeat 111..137 CDD:275381 9/25 (36%)
leucine-rich repeat 138..163 CDD:275381 8/24 (33%)
leucine-rich repeat 164..189 CDD:275381 10/24 (42%)
leucine-rich repeat 190..215 CDD:275381 3/24 (13%)
leucine-rich repeat 216..241 CDD:275381 7/24 (29%)
leucine-rich repeat 242..267 CDD:275381 7/27 (26%)
leucine-rich repeat 268..290 CDD:275381 9/21 (43%)
Fbxl2NP_848739.1 F-box-like 15..57 CDD:289689
leucine-rich repeat 52..79 CDD:275381
LRR 1 61..87
AMN1 <76..223 CDD:187754 22/88 (25%)
leucine-rich repeat 80..99 CDD:275381
Interaction with Calmodulin. /evidence=ECO:0000269|PubMed:21343341 80..90
LRR 2 88..113
leucine-rich repeat 106..131 CDD:275381
LRR 3 114..139
leucine-rich repeat 132..157 CDD:275381
LRR 4 140..165 2/5 (40%)
leucine-rich repeat 158..183 CDD:275381 8/47 (17%)
LRR 5 166..191 9/48 (19%)
AMN1 168..367 CDD:187754 60/233 (26%)
leucine-rich repeat 184..209 CDD:275381 9/25 (36%)
LRR 6 192..217 9/25 (36%)
leucine-rich repeat 210..235 CDD:275381 8/24 (33%)
LRR 7 218..243 8/24 (33%)
leucine-rich repeat 236..261 CDD:275381 10/24 (42%)
LRR 8 244..269 7/24 (29%)
leucine-rich repeat 262..287 CDD:275381 3/24 (13%)
LRR 9 270..295 4/24 (17%)
leucine-rich repeat 288..313 CDD:275381 7/24 (29%)
LRR 10 296..321 6/24 (25%)
leucine-rich repeat 314..336 CDD:275381 6/21 (29%)
LRR 11 322..350 10/27 (37%)
leucine-rich repeat 343..362 CDD:275381 8/18 (44%)
LRR 12 351..375 10/33 (30%)
LRR 13 376..401 67/252 (27%)
CAAX motif 420..423
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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