DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jet and fbxl3l

DIOPT Version :9

Sequence 1:	NP_608880.2	Gene:	jet / 33705	FlyBaseID:	FBgn0031652	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	XP_693270.2	Gene:	fbxl3l / 564855	ZFINID:	ZDB-GENE-130530-598	Length:	448	Species:	Danio rerio

Alignment Length:	250	Identity:	50/250 - (20%)
Similarity:	81/250 - (32%)	Gaps:	87/250 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 DELLLPLLANNKKRLWAVNLNECVNITALSLQPIIVECKELRVLKLS------------------ 170
            |..|..|:|||...|..:.::.|.:::...:..:..:|..||.|.|:
Zfish   206 DPSLKVLVANNSDTLKLLKMSSCPHVSPAGILCVADQCHGLRELALNYHLLSDELLLALSSEKHV 270

  Fly   171 -----------------------KCQWLTTGAVDALTLH--QSKLVEFDISYCGAIGERCLIIFF 210
                                   |..|      |||..|  |..:|.:...|     |.....||
Zfish   271 HLEHLRIDVVSENPGQTQFHTIKKSSW------DALIRHSPQVNIVMYFFLY-----EEEFEPFF 324

  Fly   211 RKLNKLTVLSLANTPSVTDQVLIQIGNYCRELEHINVIGCAAISDYGVHALTVHCLRLRTLLIRR 275
            |:...:|.|....  :|:..:|.:||..|..|  :.::.||    .|:..|....:|:..    |
Zfish   325 REETPVTHLYFGR--AVSKDMLGRIGLNCPRL--VELVVCA----NGLEPLDEELIRIAD----R 377

  Fly   276 CPRVTELSLAP------------------LRQRRLYIDRPQPDVGLNAYNLNDFY 312
            |..:|.:.|..                  |.|..:..:...||   |.||:...:
Zfish   378 CKSLTAIGLGECEVTCSGFMEFVKMCGGRLSQLSIMEEVLIPD---NTYNIEQIH 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jet	NP_608880.2	leucine-rich repeat	85..110	CDD:275381
		AMN1	96..>261	CDD:187754	37/179 (21%)
		leucine-rich repeat	111..137	CDD:275381	6/12 (50%)
		leucine-rich repeat	138..163	CDD:275381	3/24 (13%)
		leucine-rich repeat	164..189	CDD:275381	11/67 (16%)
		leucine-rich repeat	190..215	CDD:275381	6/24 (25%)
		leucine-rich repeat	216..241	CDD:275381	7/24 (29%)
		leucine-rich repeat	242..267	CDD:275381	5/24 (21%)
		leucine-rich repeat	268..290	CDD:275381	5/39 (13%)
fbxl3l	XP_693270.2	F-box-like	56..99	CDD:289689
		leucine-rich repeat	194..218	CDD:275381	6/11 (55%)
		leucine-rich repeat	220..245	CDD:275381	3/24 (13%)
		leucine-rich repeat	246..271	CDD:275381	4/24 (17%)
		leucine-rich repeat	272..306	CDD:275381	6/39 (15%)
		leucine-rich repeat	307..353	CDD:275381	13/52 (25%)
		AMN1	<347..>412	CDD:187754	15/74 (20%)
		leucine-rich repeat	354..380	CDD:275381	8/35 (23%)
		leucine-rich repeat	381..403	CDD:275381	2/21 (10%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900