DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment jet and Fbxl17

DIOPT Version :9

Sequence 1:NP_608880.2 Gene:jet / 33705 FlyBaseID:FBgn0031652 Length:319 Species:Drosophila melanogaster
Sequence 2:NP_056609.1 Gene:Fbxl17 / 50758 MGIID:1354704 Length:701 Species:Mus musculus


Alignment Length:298 Identity:73/298 - (24%)
Similarity:126/298 - (42%) Gaps:47/298 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 LVTASIAAPRSLFD--VCWDDVLIPQVAVYLSLKDLFNLRC--CSRTAQRFVEAALEKRQELHLS 90
            ::..:|:..|||.|  ||......|.:..|.:      .||  .|.|:...|.:.....|::|: 
Mouse   388 IIEINISDCRSLSDSGVCVLAFKCPGLLRYTA------YRCKQLSDTSIIAVASHCPLLQKVHV- 445

  Fly    91 GNNTKNIDVAFRVLARCCQRLEVLHLACCRWLTDELLLPLLANNKKRLWAVNLNECVNITALSLQ 155
            ||..|..|...:.|...|:.|:.:|...|..::||.:: ::|.:..:|..:.:.|...:|..|::
Mouse   446 GNQDKLTDEGLKQLGSRCRELKDIHFGQCYKISDEGMI-VIAKSCLKLQRIYMQENKLVTDQSVK 509

  Fly   156 PIIVECKELRVLKLSKCQWLTTGAVDALTLHQSKL-----------VEFD--------------- 194
            .....|.||:.:....|...:.|.:     |.:||           .|.|               
Mouse   510 AFAEHCPELQYVGFMGCSVTSKGVI-----HLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLS 569

  Fly   195 -ISYC--GAIGERCLIIFFRKLNKLTVLSLANTPSVTDQVLIQIGNYCRELEHINVIGCAAISDY 256
             ::.|  ..|.:||:.:..::...|..|.|.:. .:||..||.||.|...:|.::|..|..|:|.
Mouse   570 SLNLCLNWIINDRCVEVIAKEGQNLKELYLVSC-KITDYALIAIGRYSVTIETVDVGWCKEITDQ 633

  Fly   257 GVHALTVHCLRLRTLLIRRCPRVTELSLAPLRQRRLYI 294
            |...:......||.|.:.||.:|.||::..|.|:..:|
Mouse   634 GATLIAQSSKSLRYLGLMRCDKVNELTVEQLVQQYPHI 671

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
jetNP_608880.2 leucine-rich repeat 85..110 CDD:275381 8/24 (33%)
AMN1 96..>261 CDD:187754 43/193 (22%)
leucine-rich repeat 111..137 CDD:275381 6/25 (24%)
leucine-rich repeat 138..163 CDD:275381 5/24 (21%)
leucine-rich repeat 164..189 CDD:275381 4/24 (17%)
leucine-rich repeat 190..215 CDD:275381 7/53 (13%)
leucine-rich repeat 216..241 CDD:275381 10/24 (42%)
leucine-rich repeat 242..267 CDD:275381 6/24 (25%)
leucine-rich repeat 268..290 CDD:275381 9/21 (43%)
Fbxl17NP_056609.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 73..93
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 227..250
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 279..321
F-box-like 321..368 CDD:289689
leucine-rich repeat 362..387 CDD:275381
leucine-rich repeat 388..413 CDD:275381 7/24 (29%)
AMN1 411..573 CDD:187754 35/174 (20%)
leucine-rich repeat 414..439 CDD:275381 6/30 (20%)
leucine-rich repeat 440..465 CDD:275381 8/25 (32%)
leucine-rich repeat 466..491 CDD:275381 6/25 (24%)
leucine-rich repeat 492..517 CDD:275381 5/24 (21%)
leucine-rich repeat 545..567 CDD:275381 2/21 (10%)
leucine-rich repeat 568..593 CDD:275381 4/24 (17%)
leucine-rich repeat 594..618 CDD:275381 10/24 (42%)
leucine-rich repeat 619..644 CDD:275381 6/24 (25%)
leucine-rich repeat 645..670 CDD:275381 10/24 (42%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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