DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jet and Fbxl22

DIOPT Version :9

Sequence 1:	NP_608880.2	Gene:	jet / 33705	FlyBaseID:	FBgn0031652	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001102239.1	Gene:	Fbxl22 / 363083	RGDID:	1311830	Length:	236	Species:	Rattus norvegicus

Alignment Length:	151	Identity:	37/151 - (24%)
Similarity:	63/151 - (41%)	Gaps:	21/151 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 RCCSRTAQRFVEAALEKRQELH----LSGNNTKNIDVAFRVLARC--CQRLEVLHL--------- 116
            |.||:....|.:..|......|    |..:|.: :..|.|.|:.|  ..|::|..:
  Rat    28 RTCSQLRDVFEDPTLWSLLHFHSLTELKKDNFR-LSPALRSLSICWHSSRVQVCSIEDWLKSAFQ 91

  Fly   117 --ACCRW--LTDELLLPLLANNKKRLWAVNLNECVNITALSLQPIIVECKELRVLKLSKCQWLTT 177
              .|.:.  |.::.||. :.|....|.:|.|:.|.::|...|..:::.|..||.|:|..|..:|.
  Rat    92 RSICSQHENLVNDFLLQ-VCNRCPNLASVTLSGCGHVTDDCLARLLLGCPRLRALRLENCARVTN 155

  Fly   178 GAVDALTLHQSKLVEFDISYC 198
            ..:.|:..|...|..|.:.:|
  Rat   156 RTLAAVAAHGRALQTFHVDFC 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jet	NP_608880.2	leucine-rich repeat	85..110	CDD:275381	7/30 (23%)
		AMN1	96..>261	CDD:187754	29/118 (25%)
		leucine-rich repeat	111..137	CDD:275381	6/38 (16%)
		leucine-rich repeat	138..163	CDD:275381	7/24 (29%)
		leucine-rich repeat	164..189	CDD:275381	8/24 (33%)
		leucine-rich repeat	190..215	CDD:275381	3/9 (33%)
		leucine-rich repeat	216..241	CDD:275381
		leucine-rich repeat	242..267	CDD:275381
		leucine-rich repeat	268..290	CDD:275381
Fbxl22	NP_001102239.1	F-box-like	3..43	CDD:403981	4/14 (29%)
		AMN1	44..>191	CDD:187754	32/135 (24%)
		leucine-rich repeat	116..141	CDD:275381	7/24 (29%)
		leucine-rich repeat	142..167	CDD:275381	8/24 (33%)
		leucine-rich repeat	168..193	CDD:275381	3/9 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900