DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment jet and Fbxl6

DIOPT Version :9

Sequence 1:NP_608880.2 Gene:jet / 33705 FlyBaseID:FBgn0031652 Length:319 Species:Drosophila melanogaster
Sequence 2:NP_001005563.1 Gene:Fbxl6 / 362941 RGDID:1359687 Length:535 Species:Rattus norvegicus


Alignment Length:377 Identity:85/377 - (22%)
Similarity:135/377 - (35%) Gaps:116/377 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 AMASGGQPTRTASPRPLVTASIAAPR---SL---FDVCWDDVLIPQVAVYLSLKDLFNLRCCSRT 72
            ::|.|  ||..|.||       |.||   ||   .|..|.|.:..:|.|:     :|.|...:..
  Rat    74 SLARG--PTAVAKPR-------AKPRPEPSLDQGLDSGWGDRIPLEVLVH-----IFGLLVAAHG 124

  Fly    73 AQRFVEAALEKRQELH-----------------LSGNNTK-NIDVAFRVLARC-----------C 108
            ...|:..|....:..|                 |.|...| |:....::|| |           .
  Rat   125 PMPFLGRAARVCRHWHEATSHPSLWHTVTLSPALVGRAAKGNLKGEKKLLA-CLEWLIPNRFSQL 188

  Fly   109 QRLEVLHLACCRWLTD-ELLLPLLANNKKRLWAVNLNECVNITALSLQPIIVECKELRVLKLSKC 172
            |||.::|     |.:. ..:|.|::....||..:.|::|..:||.:|..:...|.:|..|.|...
  Rat   189 QRLTLIH-----WKSQVHSVLELVSKFCPRLTFLKLSDCHGVTAETLVMLAKACCQLHSLDLHHS 248

  Fly   173 QWLTTGAVDALTLHQSKLVEFDISY-------CGAIGERCLIIFFRKLNKLTV---LSLANTPSV 227
            ...:|..|..|....|::....::|       .||:...|.    .:|..|.|   :|..|||..
  Rat   249 MVESTAVVSFLEEAGSRMRRLWLTYSSQTTAILGALLGNCC----SQLQVLEVSAGMSCNNTPLQ 309

  Fly   228 TDQVLIQIGNYCRELEHINVIG------------------------------CAAISDYGVHALT 262
            .....:|.|  |.:|:.:.::.                              |:.:|:..:..| 
  Rat   310 LPVEALQRG--CPQLQVLRLLNLIWLPKPCGRGAPQGPGFPSLEELCLAGSTCSFVSNEVLGRL- 371

  Fly   263 VHCL-RLRTLLIRRCPRVTELSLAPL---RQRRLYIDRPQPDVGLNAYNLND 310
            :||. :||.|.:|.|.|:|...|..|   ...:||         |..|.::|
  Rat   372 LHCSPKLRLLDLRGCARITPTGLCHLPCQELEQLY---------LGLYGMSD 414

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
jetNP_608880.2 leucine-rich repeat 85..110 CDD:275381 8/53 (15%)
AMN1 96..>261 CDD:187754 43/216 (20%)
leucine-rich repeat 111..137 CDD:275381 5/26 (19%)
leucine-rich repeat 138..163 CDD:275381 7/24 (29%)
leucine-rich repeat 164..189 CDD:275381 6/24 (25%)
leucine-rich repeat 190..215 CDD:275381 5/31 (16%)
leucine-rich repeat 216..241 CDD:275381 9/27 (33%)
leucine-rich repeat 242..267 CDD:275381 6/55 (11%)
leucine-rich repeat 268..290 CDD:275381 9/24 (38%)
Fbxl6NP_001005563.1 F-box-like 105..155 CDD:289689 8/54 (15%)
AMN1 171..390 CDD:187754 51/231 (22%)
leucine-rich repeat 188..213 CDD:275381 7/29 (24%)
leucine-rich repeat 214..239 CDD:275381 7/24 (29%)
leucine-rich repeat 240..291 CDD:275381 11/54 (20%)
leucine-rich repeat 292..321 CDD:275381 10/30 (33%)
leucine-rich repeat 322..349 CDD:275381 1/26 (4%)
AMN1 <349..500 CDD:187754 19/76 (25%)
leucine-rich repeat 350..377 CDD:275381 5/27 (19%)
leucine-rich repeat 378..401 CDD:275381 9/22 (41%)
leucine-rich repeat 434..466 CDD:275381
leucine-rich repeat 467..491 CDD:275381
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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