DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment jet and Kdm2a

DIOPT Version :9

Sequence 1:NP_608880.2 Gene:jet / 33705 FlyBaseID:FBgn0031652 Length:319 Species:Drosophila melanogaster
Sequence 2:XP_038939767.1 Gene:Kdm2a / 361700 RGDID:1309419 Length:1166 Species:Rattus norvegicus


Alignment Length:355 Identity:78/355 - (21%)
Similarity:122/355 - (34%) Gaps:138/355 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly    65 NLR---------CCSRTAQRFVEAAL-------EKRQE---------LHLSGNNTKNID------ 98
            |||         |.:|..||..|..|       |:.:|         ..|:|..:...|      
  Rat   833 NLRPNPRVLMQHCPARNPQRGDEEGLGGEEEEEEEEEEDDSAEEGGAARLNGRGSWAQDGDESWM 897

  Fly    99 ------VAFRVLAR--CCQRLEVLHLACC----RWLTDELLLPLLANNKKRLWA-VNLNECVNIT 150
                  ..||.|:|  .|:.:.|     |    :|..|           ||||. ::|:.|..|.
  Rat   898 QREVWMSVFRYLSRRELCECMRV-----CKTWYKWCCD-----------KRLWTKIDLSRCKAIV 946

  Fly   151 ALSL------QPIIVECK-----------------ELRVLKLSKCQWLTTGAV------------ 180
            ..:|      ||:.::..                 .|:.|.|:.|.|....|:            
  Rat   947 PQALSGIIKRQPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLD 1011

  Fly   181 -------------DALTL--------HQSKLVEF-DISYCGA-IGERCLIIFFRKLNKLTVLSLA 222
                         |.||.        ::|||... |....|. |.:..|.:..|.:..|:.|.|:
  Rat  1012 LRWAVGIKDPQIRDLLTPPTDKPGQDNRSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLS 1076

  Fly   223 NTPSVTDQ---VLIQIGNYCR-ELEHINVIGCAAISDYGVHALTVHCLRLRTL-LIRRCPRVTEL 282
            :...:|||   :|..:|:..| .|..:|:.||..::|             :|| .:||...||.:
  Rat  1077 HCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTD-------------QTLFFLRRIANVTLI 1128

  Fly   283 SLAPLRQ-RRLYIDRPQPDVGLNA-YNLND 310
            .|...:| .|...:....|:.:|: |.|:|
  Rat  1129 DLRGCKQITRKACEHFISDLSINSLYCLSD 1158

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
jetNP_608880.2 leucine-rich repeat 85..110 CDD:275381 9/47 (19%)
AMN1 96..>261 CDD:187754 51/245 (21%)
leucine-rich repeat 111..137 CDD:275381 4/29 (14%)
leucine-rich repeat 138..163 CDD:275381 8/48 (17%)
leucine-rich repeat 164..189 CDD:275381 9/57 (16%)
leucine-rich repeat 190..215 CDD:275381 6/26 (23%)
leucine-rich repeat 216..241 CDD:275381 9/28 (32%)
leucine-rich repeat 242..267 CDD:275381 5/24 (21%)
leucine-rich repeat 268..290 CDD:275381 8/23 (35%)
Kdm2aXP_038939767.1 cupin_RmlC-like 204..304 CDD:424065
JHD 309..>344 CDD:407680
CTD_KDM2A 455..522 CDD:412025
zf-CXXC <581..614 CDD:366873
PHD_KDM2A 624..680 CDD:277113
F-box-like 900..938 CDD:403981 13/53 (25%)
leucine-rich repeat 934..958 CDD:275381 5/23 (22%)
AMN1 936..1142 CDD:187754 46/218 (21%)
leucine-rich repeat 959..982 CDD:275381 0/22 (0%)
leucine-rich repeat 983..1006 CDD:275381 6/22 (27%)
leucine-rich repeat 1007..1044 CDD:275381 6/36 (17%)
leucine-rich repeat 1045..1069 CDD:275381 5/23 (22%)
leucine-rich repeat 1070..1099 CDD:275381 9/28 (32%)
leucine-rich repeat 1100..1124 CDD:275381 9/36 (25%)
leucine-rich repeat 1125..1144 CDD:275381 5/18 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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