DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jet and CG8272

DIOPT Version :9

Sequence 1:	NP_608880.2	Gene:	jet / 33705	FlyBaseID:	FBgn0031652	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001260812.1	Gene:	CG8272 / 35875	FlyBaseID:	FBgn0033337	Length:	710	Species:	Drosophila melanogaster

Alignment Length:	292	Identity:	65/292 - (22%)
Similarity:	115/292 - (39%)	Gaps:	65/292 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 AVYLS----LKDLFNLRCCSRTAQRFVEAALEKRQELHLSGNNTKNIDVAFRVLARCCQRLEVLH 115
            |::|:    ||.|....|.:.|:...:|....:...:                    .|.|.|.:
  Fly   338 AIHLAKLKCLKSLDISNCDNLTSSGIIEGIASEENPV--------------------IQELNVSY 382

  Fly   116 LACCRWLTDELLLPLLANNKKRLWAVNLNECVN-ITALSLQPIIVECKELRVLKLSKCQWLTTGA 179
            |..|     |..:..:|:|.:.|.:::||.||| .|..::|.:|.:.:.||.|.|..|..||..|
  Fly   383 LQIC-----EECIKAIASNLRCLRSLHLNHCVNGATDEAIQSVIGQLRWLRELSLEHCSGLTDAA 442

  Fly   180 VDALTLHQ------------SKLVEFDISYCGAIGERCLIIFFRKLNKLTVLSLANTPSVTD--- 229
            :..:.:.:            |.:..|...|...:.||..:....:..|:::.|.|....|.|
  Fly   443 LTGINISKLEMSRKQSGSQVSSMDNFYPPYSNTLAERDSLAGSLQSIKISLRSKAEDEIVRDARR 507

  Fly   230 -QVLIQI--GNYCRE-------------LEHINVIGCAAISDYGVHALTVHCLRLRTLLIRRCPR 278
             |.::..  .|..||             |..:|:.||..|||..:.....| :.||.|::..|.:
  Fly   508 KQAMLAAYEMNLIREDDFEGHNIQQLRGLRSLNLRGCNKISDVSLKYGLKH-IELRRLMLSNCQQ 571

  Fly   279 VTELSLAPLRQRRLYIDRPQPDVGLNAYNLND 310
            ::.|.:..:......|:  :.|:. :.||:.|
  Fly   572 ISLLGMEAMASSCPSIE--ELDLS-DCYNITD 600

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jet	NP_608880.2	leucine-rich repeat	85..110	CDD:275381	0/24 (0%)
		AMN1	96..>261	CDD:187754	46/196 (23%)
		leucine-rich repeat	111..137	CDD:275381	7/25 (28%)
		leucine-rich repeat	138..163	CDD:275381	9/25 (36%)
		leucine-rich repeat	164..189	CDD:275381	8/36 (22%)
		leucine-rich repeat	190..215	CDD:275381	4/24 (17%)
		leucine-rich repeat	216..241	CDD:275381	6/30 (20%)
		leucine-rich repeat	242..267	CDD:275381	8/24 (33%)
		leucine-rich repeat	268..290	CDD:275381	5/21 (24%)
CG8272	NP_001260812.1	AMN1	269..440	CDD:187754	31/126 (25%)
		leucine-rich repeat	270..295	CDD:275381
		leucine-rich repeat	296..319	CDD:275381
		leucine-rich repeat	322..346	CDD:275381	2/7 (29%)
		leucine-rich repeat	347..399	CDD:275381	14/76 (18%)
		leucine-rich repeat	400..426	CDD:275381	9/25 (36%)
		leucine-rich repeat	427..535	CDD:275381	22/107 (21%)
		AMN1	515..>642	CDD:187754	21/90 (23%)
		leucine-rich repeat	536..560	CDD:275381	8/24 (33%)
		leucine-rich repeat	561..586	CDD:275381	5/24 (21%)
		leucine-rich repeat	587..612	CDD:275381	5/17 (29%)
		leucine-rich repeat	613..638	CDD:275381
		leucine-rich repeat	639..663	CDD:275381
		F-box-like	12..>44	CDD:289689
		leucine-rich repeat	129..166	CDD:275381
		leucine-rich repeat	167..192	CDD:275381
		leucine-rich repeat	193..244	CDD:275381
		C2	<231..274	CDD:301316
		leucine-rich repeat	246..269	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457945
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830