DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment jet and fbxl-1

DIOPT Version :9

Sequence 1:NP_608880.2 Gene:jet / 33705 FlyBaseID:FBgn0031652 Length:319 Species:Drosophila melanogaster
Sequence 2:NP_741248.1 Gene:fbxl-1 / 3564805 WormBaseID:WBGene00015350 Length:466 Species:Caenorhabditis elegans


Alignment Length:259 Identity:68/259 - (26%)
Similarity:113/259 - (43%) Gaps:30/259 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    60 LKDLFNLRCCSRTAQRFVEAALEKRQEL-HLSGNNTKNI-DVAFRVLARCCQRLEVLHLACCRWL 122
            ||:| :|:.|.......:.....:...| |||....|.: |.:...|.|.|.:|..|:|..|..:
 Worm   125 LKEL-SLKGCENVHDSALRTFTSRCPNLEHLSLYRCKRVTDASCENLGRYCHKLNYLNLENCSSI 188

  Fly   123 TDELLLPLLANNKKRLWAVNLNECVNITALSLQPIIVECKELRVLKLSKCQWLT----------T 177
            ||. .:..:.:....|..:|::.|..|....:|.|:..||.|..|.|..|:.||          .
 Worm   189 TDR-AMKYIGDGCPNLSYLNISWCDAIQDRGVQIILSNCKSLDTLILRGCEGLTENVFGSVEAHM 252

  Fly   178 GAVDALTLHQS-KLVEFDI---------------SYCGAIGERCLIIFFRKLNKLTVLSLANTPS 226
            ||:..|.|.|. :|.:..:               |.|..|.:|.|:...:..:.|.||.|:....
 Worm   253 GAIKKLNLLQCFQLTDITVQNIANGATALEYLCMSNCNQISDRSLVSLGQHSHNLKVLELSGCTL 317

  Fly   227 VTDQVLIQIGNYCRELEHINVIGCAAISDYGVHALTVHCLRLRTLLIRRCPRVTELSLAPLRQR 290
            :.|...|.:...||:||.:::..|:.|||:.:::|..:|..||.|.:..|..:|:.|:..|..:
 Worm   318 LGDNGFIPLARGCRQLERLDMEDCSLISDHTINSLANNCTALRELSLSHCELITDESIQNLASK 381

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
jetNP_608880.2 leucine-rich repeat 85..110 CDD:275381 9/26 (35%)
AMN1 96..>261 CDD:187754 49/191 (26%)
leucine-rich repeat 111..137 CDD:275381 6/25 (24%)
leucine-rich repeat 138..163 CDD:275381 7/24 (29%)
leucine-rich repeat 164..189 CDD:275381 11/35 (31%)
leucine-rich repeat 190..215 CDD:275381 6/39 (15%)
leucine-rich repeat 216..241 CDD:275381 7/24 (29%)
leucine-rich repeat 242..267 CDD:275381 8/24 (33%)
leucine-rich repeat 268..290 CDD:275381 7/21 (33%)
fbxl-1NP_741248.1 F-box-like 60..101 CDD:372399
AMN1 <121..268 CDD:187754 40/144 (28%)
leucine-rich repeat 125..150 CDD:275381 5/25 (20%)
leucine-rich repeat 151..176 CDD:275381 9/24 (38%)
leucine-rich repeat 177..202 CDD:275381 6/25 (24%)
leucine-rich repeat 203..228 CDD:275381 7/24 (29%)
leucine-rich repeat 229..280 CDD:275381 12/50 (24%)
AMN1 <281..440 CDD:187754 28/101 (28%)
leucine-rich repeat 281..306 CDD:275381 5/24 (21%)
leucine-rich repeat 307..332 CDD:275381 7/24 (29%)
leucine-rich repeat 333..357 CDD:275381 7/23 (30%)
leucine-rich repeat 359..384 CDD:275381 7/23 (30%)
leucine-rich repeat 386..409 CDD:275381
leucine-rich repeat 411..436 CDD:275381
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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