DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment jet and Fbxl13

DIOPT Version :9

Sequence 1:NP_608880.2 Gene:jet / 33705 FlyBaseID:FBgn0031652 Length:319 Species:Drosophila melanogaster
Sequence 2:XP_011248071.1 Gene:Fbxl13 / 320118 MGIID:2443416 Length:889 Species:Mus musculus


Alignment Length:276 Identity:73/276 - (26%)
Similarity:118/276 - (42%) Gaps:73/276 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 RSLFDVCWDDVL----IPQVAVYLSLKDLFNLRCCSRTAQRFVEAALEKRQEL--HLSGNNTKNI 97
            |..||:   .||    |.|:.:||:.||:.   .|||..:.::  |:.:|..|  .:..:..|||
Mouse   235 RIAFDI---SVLPEQAILQIFLYLTFKDMM---ACSRVNRSWM--AMIQRGSLWNSIDFSTVKNI 291

  Fly    98 DVAFRVLARCCQ--RLEVLHL--ACCRWLTDELLLPLLANNKKRLWAVNLNECVNITALSLQPII 158
              |.:.:....|  ||.||.|  ..|.:.|..|   ...::.|.|..:|:::|.:.|..|::.|.
Mouse   292 --ADKCVVTTLQKWRLNVLRLNFRGCDFRTKTL---KAVSHCKNLQELNVSDCQSFTDESMRHIS 351

  Fly   159 VECKELRVLKLSKCQWLTTGAVDALTLHQSKLVEFDISYCGAIGERCLIIFFRKLNKLTVLSLAN 223
            ..|..:..|.||.    ||                       |..|.:.:..|..:.|..||||.
Mouse   352 EGCPGVLYLNLSN----TT-----------------------ITNRTMRLLPRYFHNLQNLSLAY 389

  Fly   224 TPSVTDQVL--IQIGNYCRELEHINVIGCAAISDYG-----------VH-------ALTVHCLRL 268
            ....||:.|  :.:||.|.:|.::::.||..||..|           ||       .||.:|:: 
Mouse   390 CRKFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRNIASSCTGIVHLTINDMPTLTDNCVK- 453

  Fly   269 RTLLIRRCPRVTELSL 284
              :|:.:|||::.:.|
Mouse   454 --VLVEKCPRISSVVL 467

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
jetNP_608880.2 leucine-rich repeat 85..110 CDD:275381 6/28 (21%)
AMN1 96..>261 CDD:187754 47/188 (25%)
leucine-rich repeat 111..137 CDD:275381 7/27 (26%)
leucine-rich repeat 138..163 CDD:275381 7/24 (29%)
leucine-rich repeat 164..189 CDD:275381 5/24 (21%)
leucine-rich repeat 190..215 CDD:275381 3/24 (13%)
leucine-rich repeat 216..241 CDD:275381 11/26 (42%)
leucine-rich repeat 242..267 CDD:275381 11/42 (26%)
leucine-rich repeat 268..290 CDD:275381 5/17 (29%)
Fbxl13XP_011248071.1 F-box-like 240..284 CDD:372399 14/51 (27%)
leucine-rich repeat 255..268 CDD:275381 6/15 (40%)
leucine-rich repeat 280..306 CDD:275381 6/27 (22%)
AMN1 306..475 CDD:187754 49/195 (25%)
leucine-rich repeat 307..330 CDD:275381 6/25 (24%)
leucine-rich repeat 331..356 CDD:275381 7/24 (29%)
leucine-rich repeat 357..381 CDD:275381 8/50 (16%)
leucine-rich repeat 382..409 CDD:275381 11/26 (42%)
leucine-rich repeat 410..435 CDD:275381 6/24 (25%)
leucine-rich repeat 436..461 CDD:275381 7/27 (26%)
leucine-rich repeat 462..484 CDD:275381 1/6 (17%)
AMN1 473..605 CDD:187754
leucine-rich repeat 486..511 CDD:275381
leucine-rich repeat 512..536 CDD:275381
leucine-rich repeat 537..564 CDD:275381
leucine-rich repeat 565..590 CDD:275381
leucine-rich repeat 591..610 CDD:275381
leucine-rich repeat 617..645 CDD:275381
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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