DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jet and Fbxl17

DIOPT Version :9

Sequence 1:	NP_608880.2	Gene:	jet / 33705	FlyBaseID:	FBgn0031652	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	XP_038939705.1	Gene:	Fbxl17 / 316663	RGDID:	1309773	Length:	739	Species:	Rattus norvegicus

Alignment Length:	240	Identity:	56/240 - (23%)
Similarity:	104/240 - (43%)	Gaps:	58/240 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 IPQVAVYLSLKDLFNL----RCCSRTAQRFVEAALEKR--QELHLSGNNTKNIDVAFRVLARCCQ 109
            |.|:...:.||...||    ||.|        |:|..:  ::|.|.....|.:|::.|
  Rat   316 INQLPPSILLKIFSNLSLDERCLS--------ASLVCKYWRDLCLDFQFWKQLDLSSR------- 365

  Fly   110 RLEVLHLACCRWLTDELLLPLLANNKKRLWAVNLNECVNITALSLQPIIVECKELRVLKLSKCQW 174
                      :.:||| ||..:|:..:.:..:|:::|.:::...:..:..:|..|......:|:.
  Rat   366 ----------QQVTDE-LLEKIASRSQNIVEINISDCRSMSDSGVCVLAFKCPGLLRYTAYRCKQ 419

  Fly   175 LTTGAVDALTLHQSKLVEFDISYCGAIGERCLIIFFRKLNKLTVLSLANTPSVTDQVLIQIGNYC 239
            |:..::.|:..|                  |.:     |.|:.|   .|...:||:.|.|:|:.|
  Rat   420 LSDTSIIAVASH------------------CPL-----LQKVHV---GNQDKLTDEGLKQLGSKC 458

  Fly   240 RELEHINVIGCAAISDYGVHALTVHCLRLRTLLIRRCPRVTELSL 284
            |||:.|:...|..|||.|:..:...||:|:.:.::....||:.|:
  Rat   459 RELKDIHFGQCYKISDEGMVVIAKSCLKLQRIYMQENKLVTDQSV 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jet	NP_608880.2	leucine-rich repeat	85..110	CDD:275381	5/24 (21%)
		AMN1	96..>261	CDD:187754	36/164 (22%)
		leucine-rich repeat	111..137	CDD:275381	6/25 (24%)
		leucine-rich repeat	138..163	CDD:275381	3/24 (13%)
		leucine-rich repeat	164..189	CDD:275381	5/24 (21%)
		leucine-rich repeat	190..215	CDD:275381	2/24 (8%)
		leucine-rich repeat	216..241	CDD:275381	8/24 (33%)
		leucine-rich repeat	242..267	CDD:275381	8/24 (33%)
		leucine-rich repeat	268..290	CDD:275381	4/17 (24%)
Fbxl17	XP_038939705.1	F-box-like	316..361	CDD:403981	14/52 (27%)
		leucine-rich repeat	357..382	CDD:275381	9/42 (21%)
		leucine-rich repeat	383..408	CDD:275381	3/24 (13%)
		AMN1	406..568	CDD:187754	32/124 (26%)
		leucine-rich repeat	409..434	CDD:275381	6/42 (14%)
		leucine-rich repeat	435..460	CDD:275381	10/27 (37%)
		leucine-rich repeat	461..486	CDD:275381	8/24 (33%)
		leucine-rich repeat	487..512	CDD:275381	4/17 (24%)
		leucine-rich repeat	513..536	CDD:275381
		leucine-rich repeat	537..562	CDD:275381
		leucine-rich repeat	563..588	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900